This gene encodes a tetratricopeptide repeat domain-containing protein. The encoded protein interacts with estrogen receptors and the heat shock proteins, Hsp70 and Hsp90. A chromosomal translocation involving this gene is associated with a susceptibility to developmental dyslexia. Mutations in this gene are associated with deficits in reading and spelling. Alternate splicing results in multiple transcript variants.
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Protein Aliases: Dynein axonemal assembly factor 4; dynein, axonemal, assembly factor 4; Dyslexia susceptibility 1 candidate gene 1 protein; Dyslexia susceptibility 1 candidate gene 1 protein homolog; FLJ37882; MGC70618
Gene Aliases: 1700010I24Rik; b2b811Clo; CILD25; DNAAF4; DYX1; DYX1C1; DYXC1; EKN1; RD
Molecular Function: chaperone