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Invitrogen
Decapentaplegic Polyclonal Antibody
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Product Details
PA5-148509
Product Specifications
Species Reactivity
Fruit fly
Host/Isotype
Chicken
/ IgY
Class
Polyclonal
Type
Antibody
Immunogen
E. coli-derived recombinant Drosophila Decapentaplegic/DPP, Asp457-Arg588 (Gln473His, Pro474Ala)
Conjugate
Form
Lyophilized
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with trehalose
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitute at 0.2 mg/mL in sterile PBS.
Target Information
Decapentaplegic (Dpp) is a gene in Drosophila melanogaster, encoding a protein that is a member of the Transforming Growth Factor-beta (TGF-beta) superfamily. Dpp plays a crucial role in various developmental processes, including embryogenesis, organogenesis, and the regulation of cell growth and differentiation. It functions primarily as a morphogen, a signaling molecule that forms a concentration gradient to provide positional information to cells, guiding their development and differentiation. Dpp is essential for the proper patterning of tissues and organs, such as the wings, legs, and gut in fruit flies. Mutations in the Dpp gene can lead to severe developmental abnormalities and defects in tissue patterning. The study of Dpp and its signaling pathways provides valuable insights into the mechanisms of morphogen-mediated development and has broader implications for understanding similar TGF-beta signaling pathways in other organisms, including humans.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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