Invitrogen

Desmoglein 2 (DSG2) Polyclonal Antibody

View all (28) Desmoglein 2 (DSG2) antibodies

Datasheet

Protocols

Questions & Answers

Tech Support

Datasheet

Protocols

Questions & Answers

Tech Support

Product Image Gallery

Desmoglein 2 (DSG2) Antibody in Western Blot (WB) — Western blot analysis of Desmoglein 2 (DSG2) in Lane 1: HT1080 whole cell lysate, Lane 2: HeLa whole cell lysate, Lane 3: SW620 whole cell lysate, Lane 4: SCG whole cell lysate, Lane 5: COLO320 whole cell lysate using 40-50 µg per well. Sample was incubated with Desmoglein 2 (DSG2) (Product # PA5-79171) at a dilution of 0.5 µg/mL.

Product Details

PA5-79171

Applications	Tested Dilution	Publications
Western Blot (WB)	0.1-0.5 µg/mL	-
Immunohistochemistry (Paraffin) (IHC (P))	0.5-1 µg/mL	-
Immunocytochemistry (ICC/IF)	2 µg/mL	-
Flow Cytometry (Flow)	1-3 µg/1x10^6 cells	-

Product Specifications
Species Reactivity	Human, Mouse, Rat
Host/Isotype	Rabbit / IgG
Class	Polyclonal
Type	Antibody
Immunogen	A synthetic peptide corresponding to a sequence at the C-terminus of human Desmoglein 2 (1104-1118aa STRVTKHSTVQHSYS). View immunogen
Conjugate	Unconjugated
Form	Lyophilized
Concentration	500 µg/mL
Purification	Antigen affinity chromatography
Storage buffer	PBS with 5mg BSA
Contains	0.05mg sodium azide, 0.05mg thimerosal
Storage conditions	-20°C
RRID	AB_2746287

Product Specific Information

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.

Target Information

Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This protein has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus vulgaris.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.