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|Tested species reactivity||Bacteria|
|Host / Isotype||Goat / IgG|
|Immunogen||Purified diphtheria toxoid.|
|Storage buffer||PBS, pH 7.2|
|Contains||0.1% sodium azide|
|Storage Conditions||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C|
|Tested Applications||Dilution *|
|ELISA (ELISA)||Assay dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA1-7212 detects diphtheria toxin.
PA1-7212 has been successfully used in ELISA procedures.
The PA1-7212 immunogen is purified diphtheria toxoid.
For longer term storage, aliquot and freeze at -20°C.
Corynebacterium diphtheriae infects the nasopharynx or skin, multiplying and secreting diphtheria toxin in nasopharyngeal or skin lesions. The diphtheria toxin is exceptionally potent with as little as 100-150 ng/kg of body weight being a lethal dose in susceptible individuals. Diphtheria toxin expression is under the control of an iron-activated repressor, DtxR. The dissociation of iron and DtxR under low iron conditions activates the tox gene, leading to its synthesis and secretion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.