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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • Dnmt2 Antibodies

          Fabgennix

          Dnmt2 Polyclonal Antibody, FITC

          View all (16) Dnmt2 antibodies

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          Cite Dnmt2 Polyclonal Antibody, FITC

          Dnmt2 Polyclonal Antibody, FITC

          Product Details

          DNMT2-FITC

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500
          -

          ELISA (ELISA)

          1:10,000
          -

          Immunoprecipitation (IP)

          1:200
          -
          Product Specifications

          Species Reactivity

          Mouse, Rat

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Synthetic peptide corresponding to amino acids within region 350-400 on mouse tRNA (cytosine(38)-C(5))-methyltransferase protein.
          View immunogen

          Conjugate

          FITC FITC FITC

          Excitation/Emission Max

          498/517 nm View spectra spectra

          Form

          Liquid

          Concentration

          0.5-1.5 mg/mL

          Purification

          Affinity chromatography

          Storage buffer

          proprietary buffer with 20% glycerol, 0.5% BSA

          Contains

          0.01% sodium azide

          Storage conditions

          -20°C, Avoid Freeze/Thaw Cycles, store in dark

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          Product Specific Information

          Quantity: 100 µg IgG per vial

          Target Information

          CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a protein with similarity to DNA methyltransferases, but this protein does not display methyltransferase activity. The protein strongly binds DNA, suggesting that it may mark specific sequences in the genome. Alternative splicing results in multiple transcript variants encoding different isoforms.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: DNA (cytosine-5)-methyltransferase-like protein 2; DNA methyltransferase 2; DNA methyltransferase homolog MmuIIP; DNA MTase homolog MmuIIP; Dnmt2; M.HsaIIP; m.MmuIIP; Met-2; RP11-406H21.1; tRNA (cytosine(38)-C(5))-methyltransferase; tRNA (cytosine-5-)-methyltransferase

          View more View less

          Gene Aliases: Dnmt2; Met2; Rnmt2; Trdmt1

          View more View less

          UniProt ID: (Mouse) O55055, (Rat) Q4G073

          View more View less

          Entrez Gene ID: (Mouse) 13434, (Rat) 291324

          View more View less

          Function(s)
          DNA binding RNA binding methyltransferase activity tRNA methyltransferase activity transferase activity molecular_function RNA metabolism protein RNA processing factor nucleic acid metabolism protein
          Process(es)
          DNA methylation tRNA processing tRNA methylation methylation response to amphetamine
          It has to be done as per old AB suggested Products section.
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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

          Learn more
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          We're here to help

          Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

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