The antibody detects endogenous levels of total TDP2 protein.
This gene encodes a member of a superfamily of divalent cation-dependent phosphodiesterases. The encoded protein associates with CD40, tumor necrosis factor (TNF) receptor-75 and TNF receptor associated factors (TRAFs), and inhibits nuclear factor-kappa-B activation. This protein has sequence and structural similarities with APE1 endonuclease, which is involved in both DNA repair and the activation of transcription factors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 5'-Tyr-DNA phosphodiesterase; 5'-tyrosyl-DNA phosphodiesterase; APII; EAPII; ETS1-associated protein 2; ETS1-associated protein II; TRAF and TNF receptor associated protein; TRAF and TNF receptor-associated protein; TS1-associated protein 2; TS1-associated protein II; Tyr-DNA phosphodiesterase 2; Tyrosyl-DNA phosphodiesterase 2; Tyrosyl-RNA phosphodiesterase; VPg unlinkase
Gene Aliases: AD-022; AD022; D13Ertd656e; dJ30M3.3; EAP2; EAPII; hTDP2; TDP2; TTRAP