PA5-28768 targets EDG2 in WB applications and shows reactivity with Human samples.
The PA5-28768 immunogen is synthetic peptide corresponding to a region within amino acids 300 and 364 of Human EDG2.
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The integral membrane protein encoded by this gene is a lysophosphatidic acid (LPA) receptor from a group known as EDG receptors. These receptors are members of the G protein-coupled receptor superfamily. Utilized by LPA for cell signaling, EDG receptors mediate diverse biologic functions, including proliferation, platelet aggregation, smooth muscle contraction, inhibition of neuroblastoma cell differentiation, chemotaxis, and tumor cell invasion. Two transcript variants encoding the same protein have been identified for this gene
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Protein Aliases: 2; edg-2; EDG2; endothelial differentiation; endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 2; Gpcr26; GPR26; LPA receptor 1; LPA-1; LPA1; lysophosphatidic acid G-protein-coupled receptor; Lysophosphatidic acid receptor 1; Lysophosphatidic acid receptor Edg-2; Mrec1.3; rec.1.3; ventricular zone gene 1; vzg-1; VZG1
Gene Aliases: edg-2; EDG2; Gpcr26; GPR26; LPA1; LPAR1; Mrec1.3; rec.1.3; vzg-1; VZG1
UniProt ID: (Human) Q92633
Entrez Gene ID: (Human) 1902