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Proteintech
EDNRB Recombinant Rabbit Monoclonal Antibody (1O2), CoraLite® Plus 750
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Product Details
CL750-82818-2
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
CHO cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
1O2
Immunogen
Peptide
Conjugate
Excitation/Emission Max
755/780 nm
Form
Liquid
Concentration
1000 µg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 0.5% BSA, 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
-20°C, store in dark
Shipping conditions
Wet ice
Target Information
Non-specific receptor for endothelin 1, 2, and 3. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: AU022549; endothelin B receptor; Endothelin receptor non-selective type; endothelin receptor subtype B1; Endothelin receptor type B; endothelin-B receptor; ET-B; Et-b receptor; Et-b-r; ET-BR; ET-RB; Etb receptor; Etb-svr; G-protein coupled receptor; Hirschsprung disease 2; piebald; RP11-318G21.1; unnamed protein product
Gene Aliases: ABCDS; Ednra; EDNRB; ET-B; ET-BR; ETB; ETB1; ETBR; ETR-b; ETRB; HSCR; HSCR2; Sox10m1; WS4A
UniProt ID: (Human) P24530, (Rat) P21451, (Mouse) P48302
Entrez Gene ID: (Human) 1910, (Rat) 50672, (Mouse) 13618
negative regulation of transcription from RNA polymerase II promoter
neural crest cell migration
renin secretion into blood stream
regulation of heart rate
regulation of pH
signal transduction
cell surface receptor signaling pathway
G-protein coupled receptor signaling pathway
negative regulation of adenylate cyclase activity
phospholipase C-activating G-protein coupled receptor signaling pathway
positive regulation of cytosolic calcium ion concentration
nervous system development
peripheral nervous system development
posterior midgut development
regulation of blood pressure
positive regulation of cell proliferation
gene expression
negative regulation of neuron maturation
vein smooth muscle contraction
vascular smooth muscle contraction
calcium-mediated signaling
cGMP-mediated signaling
heparin metabolic process
melanocyte differentiation
regulation of fever generation
aldosterone metabolic process
response to lipopolysaccharide
enteric smooth muscle cell differentiation
positive regulation of urine volume
renal sodium excretion
epithelial fluid transport
vasoconstriction
vasodilation
negative regulation of apoptotic process
positive regulation of I-kappaB kinase/NF-kappaB signaling
pigmentation
developmental pigmentation
macrophage chemotaxis
response to pain
enteric nervous system development
regulation of epithelial cell proliferation
negative regulation of protein metabolic process
sodium ion homeostasis
canonical Wnt signaling pathway
positive regulation of penile erection
establishment of endothelial barrier
renal sodium ion absorption
calcium ion transmembrane transport
cellular response to lipopolysaccharide
protein transmembrane transport
glomerular visceral epithelial cell differentiation
endothelin receptor signaling pathway
renal albumin absorption
neuroblast migration
chordate pharynx development
response to sodium phosphate
response to endothelin
positive regulation of protein phosphorylation
aging
response to organic cyclic compound
sensory perception of pain
negative regulation of cellular protein metabolic process
positive regulation of renal sodium excretion
regulation of sensory perception of pain
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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