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Fabgennix
EFEMP1 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
EFP-101AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Non-human primate,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic cyclic peptide corresponding to N terminal amino acids 25-42 of Human EFEMP1, peptide was covalently modified. Sequence:TYTQCTDGYEWDPVRQQC.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.5-1.5 mg/mL
Purification
Affinity chromatography
Storage buffer
proprietary buffer, pH 7.4-7.8, with 30% glycerol, 0.5% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
This gene encodes a member of the fibulin family of extracellular matrix glycoproteins. Like all members of this family, the encoded protein contains tandemly repeated epidermal growth factor-like repeats followed by a C-terminus fibulin-type domain. This gene is upregulated in malignant gliomas and may play a role in the aggressive nature of these tumors. Mutations in this gene are associated with Doyne honeycomb retinal dystrophy. Alternatively spliced transcript variants that encode the same protein have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: EGF containing fibulin extracellular matrix protein 1; EGF containing fibulin like extracellular matrix protein 1; epidermal growth factor-containing fibulin-like extracellular matrix protein 1; extracellular protein S1-5; FIBL-3; fibulin-3; FLJ35535; glaucoma 1, open angle, H (adult-onset); MGC111353; unnamed protein product
Gene Aliases: ARCL1D; DHRD; DRAD; FBLN3; FBNL; FIBL-3; GLC1H; MLVT; MTLV; S1-5; T16
UniProt ID: (Human) Q12805, (Mouse) Q8BPB5
Entrez Gene ID: (Human) 2202, (Rat) 305604, (Mouse) 216616
regulation of transcription, DNA-templated
epidermal growth factor receptor signaling pathway
positive regulation of cell proliferation
negative regulation of neuron projection development
peptidyl-tyrosine phosphorylation
positive regulation of cell projection organization
negative regulation of chondrocyte differentiation
camera-type eye development
embryonic eye morphogenesis
post-embryonic eye morphogenesis
regulation of glial cell migration
visual perception
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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