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Docking protein which plays a central coordinating role for tyrosine-kinase-based signaling related to cell adhesion. May serve as an activator of SRC and a downstream effector. Interacts with the SH3 domain of FYN and with CRK, SRC, and YES.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Cas scaffolding protein family member 3; Embryonal Fyn-associated substrate; hEFS; signal transduction protein (SH3 containing); Signal-integrating protein; SRC-interacting protein
Gene Aliases: CAS3; CASS3; EFS; EFS1; EFS2; HEFS; SIN
UniProt ID: (Human) O43281, (Mouse) Q64355
Entrez Gene ID: (Human) 10278, (Mouse) 13644, (Rat) 290212
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