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Proteintech
EIF4A2 Polyclonal Antibody
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Product Details
11280-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse,
Pig
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
EIF4A2 Fusion Protein Ag1810 (108-407 aa encoded by BC015842)
Conjugate
Form
Liquid
Concentration
0.13 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: APTRELAQQ IQKVILALGD YMGATCHACI GGTNVRNEMQ KLQAEAPHIV VGTPGRVFDM LNRRYLSPKW IKMFVLDEAD EMLSRGFKDQ IYEIFQKLNT SIQVVLLSAT MPTDVLEVTK KFMRDPIRIL VKKEELTLEG IKQFYINVER EEWKLDTLCD LYETLTITQA VIFLNTRRKV DWLTEKMHAR DFTVSALHGD MDQKERDVIM REFRSGSSRV LITTDLLARG IDVQQVSLVI NYDLPTNREN YIHRIGRGGR FGRKGVAINF VTEEDKRILR DIETFYNTTV EEMPMNVADL I (108-407 aa encoded by BC015842)
Target Information
eIF4A2 is a 407 amino acid ATP-dependent RNA helicase belonging to the DEAD box helicase family. It contains one helicase ATP-binding domain and a helicase C-terminal domain. eIF4A2, a subunit of the eIF4F complex, acts as a protein-synthesis initiation factor and thus plays an important role in the binding of mRNA to the 43S pre-initiation complex of ribosomes. Human eIF4A2 interacts with the NS5B protein of Hepatitis C virus (HCV) and facilitates the genomic RNA synthesis of NS5B protein by unwinding the secondary structure of the HCV genome. It is ubiquitously expressed in most of normal tissues, but in variable amounts.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: ATP dependent RNA helicase eIF4A 2; ATP-dependent RNA helicase eIF4A-2; eIF-4A-II; eIF4A-II; Eukaryotic initiation factor 4A-II; eukaryotic translation initiation factor 4A isoform 2; eukaryotic translation initiation factor 4A, isoform 2; N-terminally processed; protein synthesis initiation factor 4AII
Gene Aliases: 4833432N07Rik; BM-010; DDX2B; eIF-4A-II; Eif4; EIF4A; eIF4A-II; EIF4A2; EIF4F
UniProt ID: (Human) Q14240, (Mouse) P10630, (Rat) Q5RKI1
Entrez Gene ID: (Human) 1974, (Mouse) 13682, (Rat) 303831
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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