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FIGURE: 1 / 3
Antibody detects endogenous levels of total eIF4ENIF1.
The protein encoded by this gene is a nucleocytoplasmic shuttle protein for the translation initiation factor eIF4E. This shuttle protein interacts with the importin alpha-beta complex to mediate nuclear import of eIF4E. It is predominantly cytoplasmic; its own nuclear import is regulated by a nuclear localization signal and nuclear export signals. Multiple transcript variants encoding different isoforms have been found for this gene.
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Protein Aliases: 2610509L04Rik; 4E-T; CD40 ligand-activated specific transcript 4; eIF4E transporter; eIF4E-transporter; Eukaryotic translation initiation factor 4E nuclear import factor 1; Eukaryotic translation initiation factor 4E transporter; FLJ21601; FLJ26551; OTTHUMP00000063276
Gene Aliases: 2610509L04Rik; 4E-T; A930019J01Rik; AA410001; AU021239; Clast4; D11Ertd166e; EIF4ENIF1; RGD1560908
UniProt ID: (Human) Q9NRA8, (Mouse) Q9EST3
Entrez Gene ID: (Human) 56478, (Mouse) 74203, (Rat) 305468
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