This antibody is predicted to react with bovine, canine and porcine based on sequence homology.
KLF1 is a hematopoietic-specific transcription factor that induces high-level expression of adult beta-globin and other erythroid genes. The zinc-finger protein binds to the DNA sequence CCACACCCT found in the beta hemoglobin promoter. Heterozygous loss-of-function mutations in this gene result in the dominant Inblood phenotype.
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Protein Aliases: EKLF; Erythroid krueppel-like transcription factor; erythroid Kruppel-like factor; erythroid-specific transcription factor EKLF; Krueppel-like factor 1; Kruppel-like factor 1 (erythroid); monoclonal antibody A3D8; truncated EKLF; truncated erythroid Kruppel-like factor 1
Gene Aliases: CDAN4; EKLF; HBFQTL6; INLU; KLF1
UniProt ID: (Human) Q13351
Entrez Gene ID: (Human) 10661