Immunogen sequence: ATCEISNIFS NYFSAMYSSE DSTLASVPPA ATFGADDLVL TLSNPQMSLE GTEKASWLGE QPQFWSKTQV LDWISYQVEK NKYDASAIDF SRCDMDGATL CNCALEELRL VFGPLGDQLH AQLRDLTSSS SDELSWIIEL LEKDGMA
ESE-1 (Epithelium-Specific Ets) is a novel, highly tissue-restricted member of the ets transcription factor/oncogene family, which has features distinct from those of any other ets-related factor. ESE-1 binds with high affinity to and transactivates the ets binding site in the promoter of the keratinocyte terminal differentiation marker gene, SPRR2A. ESE-1 is a critical regulator of epithelial cell differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: E74-like factor 3; E74-like factor 3 (ets domain transcription factor); E74-like factor 3 (ets domain transcription factor, epithelial-specific ); E74-like factor 3 (ETS domain transcription factor, serine box, epithelial-specific); ELF3; Epithelial-restricted with serine box; Epithelium-restricted Ets protein ESX; Epithelium-specific Ets transcription factor 1; EPR-1; ESE-1; ESX; ets domain transcription factor, serine box (epithelial-specific); ETS-related transcription factor Elf-3
Gene Aliases: ELF3; EPR-1; ERT; ESE-1; ESX; JEN
UniProt ID: (Human) P78545
Entrez Gene ID: (Human) 1999