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The ELK4 gene is a member of the Ets family of transcription factors and of the ternary complex factor (TCF) subfamily. Proteins of the TCF subfamily form a ternary complex by binding to the serum response factor and the serum response element in the promoter of the c-fos proto-oncogene. The protein encoded by ELK4 is phosphorylated by the kinases, MAPK1 and MAPK8. This gene is a member of the Ets family of transcription factors and of the ternary complex factor (TCF) subfamily. Proteins of the TCF subfamily form a ternary complex by binding to the serum response factor and the serum response element in the promoter of the c-fos proto-oncogene. The protein encoded by this gene is phosphorylated by the kinases, MAPK1 and MAPK8. Several transcript variants have been described for this gene.
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Protein Aliases: ELK4, ETS-domain protein (SRF accessory protein 1); ELK4, member of ETS oncogene family; ETS domain-containing protein Elk-4; SAP-1; Serum response factor accessory protein 1; SRF accessory protein 1
Gene Aliases: 2310011G17Rik; A130026I01Rik; BB162516; ELK4; SAP-1; SAP1
UniProt ID: (Human) P28324, (Mouse) P41158
Entrez Gene ID: (Human) 2005, (Mouse) 13714, (Rat) 304786
Molecular Function: winged helix/forkhead transcription factor
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