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Product Details
PA5-28406
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to a region within amino acids 664 and 727 of Human ELMO1
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 10% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2545882
Product Specific Information
Recommended positive controls: A431, H1299, HeLa, HepG2, N2a, PC-12, Neuro 2A, GL261, C8D30, NIH-3T3, BCL-1, Raw264.7, C2C12.^M
^M
Predicted reactivity: Mouse (100%), Rat (100%), Zebrafish (100%), Chicken (100%), Rhesus Monkey (100%), Bovine (100%).^M
^M
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The protein encoded by this gene interacts with the dedicator of cyto-kinesis 1 protein to promote phagocytosis and effect cell shape changes. Similarity to a C. elegans protein suggests that this protein may function in apoptosis and in cell migration. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: ced-12 homolog 1; engulfment and cell motility 1 splice 1; engulfment and cell motility 1, ced-12 homolog; Engulfment and cell motility protein 1; MGC126406; OTTHUMP00000207056; OTTHUMP00000207060; Protein ced-12 homolog
Gene Aliases: 6330578D22Rik; C230095H21Rik; CED-12; CED12; ELMO-1; ELMO1; ELMO1s; KIAA0281
UniProt ID: (Human) Q92556, (Mouse) Q8BPU7
Entrez Gene ID: (Human) 9844, (Mouse) 140580, (Rat) 361251
phagocytosis, engulfment
apoptotic process
movement of cell or subcellular component
cell migration
Rac protein signal transduction
actin cytoskeleton organization
Fc-gamma receptor signaling pathway involved in phagocytosis
positive regulation of GTPase activity
vascular endothelial growth factor receptor signaling pathway
regulation of defense response to virus by virus
phagocytosis
actin filament-based process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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