FIGURE: 1 / 8
Recommended positive controls: A431, H1299, HeLa, HepG2, N2a, PC-12, Neuro 2A, GL261, C8D30, NIH-3T3, BCL-1, Raw264.7, C2C12.
Predicted reactivity: Mouse (100%), Rat (100%), Zebrafish (100%), Chicken (100%), Rhesus Monkey (100%), Bovine (100%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
The protein encoded by this gene interacts with the dedicator of cyto-kinesis 1 protein to promote phagocytosis and effect cell shape changes. Similarity to a C. elegans protein suggests that this protein may function in apoptosis and in cell migration. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms.
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Protein Aliases: ced-12 homolog 1; engulfment and cell motility 1 splice 1; engulfment and cell motility 1, ced-12 homolog; Engulfment and cell motility protein 1; MGC126406; OTTHUMP00000207056; OTTHUMP00000207060; Protein ced-12 homolog
Gene Aliases: 6330578D22Rik; C230095H21Rik; CED-12; CED12; ELMO-1; ELMO1; ELMO1s; KIAA0281
Molecular Function: scaffold/adaptor protein