ELOVL2 could be implicated in tissue-specific synthesis of very long chain fatty acids and sphingolipids. This protein may catalyze one or both of the reduction reaction in fatty acid elongation, i. e., conversion of beta-ketoacyl CoA to beta-hydroxyacyl CoA or reduction of trans-2-enoyl CoA to the saturated acyl CoA derivative.
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Protein Aliases: 3-keto acyl-CoA synthase ELOVL2; elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 2; Elongation of very long chain fatty acids protein 2; ELOVL FA elongase 2; ELOVL fatty acid elongase 2; Very long chain 3-ketoacyl-CoA synthase 2; Very long chain 3-oxoacyl-CoA synthase 2; very-long-chain 3-oxoacyl-CoA synthase 2
Gene Aliases: ELG3; ELOVL2; SSC2
UniProt ID: (Human) Q9NXB9
Entrez Gene ID: (Human) 54898