Applications | Tested Dilution | Publications |
---|---|---|
Western Blot (WB) |
0.2-2 µg/mL | - |
Immunohistochemistry (Paraffin) (IHC (P)) |
5-20 µg/mL | - |
Immunocytochemistry (ICC/IF) |
5-20 µg/mL | - |
Product Specifications | |
---|---|
Species Reactivity |
Rat |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
Recombinant protein Ectonucleotide Pyrophosphatase/Phosphodiesterase 1 |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
500 µg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS with 50% glycerol |
Contains |
0.05% Proclin 300 |
Storage conditions |
-20°C |
This gene is a member of the ecto-nucleotide pyrophosphatase/phosphodiesterase (ENPP) family. The encoded protein is a type II transmembrane glycoprotein comprising two identical disulfide-bonded subunits. This protein has broad specificity and cleaves a variety of substrates, including phosphodiester bonds of nucleotides and nucleotide sugars and pyrophosphate bonds of nucleotides and nucleotide sugars. This protein may function to hydrolyze nucleoside 5' triphosphates to their corresponding monophosphates and may also hydrolyze diadenosine polyphosphates. Mutations in this gene have been associated with 'idiopathic' infantile arterial calcification, ossification of the posterior longitudinal ligament of the spine (OPLL), and insulin resistance.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Alkaline phosphodiesterase I; E-NPP 1; Ectonucleotide pyrophosphatase/phosphodiesterase family member 1; Ectonucleotide pyrophosphatase/phosphodiesterase family member 1, secreted form; HGNC:3356; NPPase; Nucleotide diphosphatase; Nucleotide pyrophosphatase; OTTHUMP00000043194; Phosphodiesterase I/nucleotide pyrophosphatase 1; Plasma-cell membrane glycoprotein PC-1
Gene Aliases: Enpp1; Npps; Pc1; Pdnp1
UniProt ID: (Rat) Q924C3
Entrez Gene ID: (Rat) 85496
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