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EPM2A Antibody (H00007957-D01P) in WB
Western Blot analysis of EPM2A expression in transfected 293T cell line (H00007957-T02) by EPM2A MaxPab polyclonal antibody.
Lane 1: EPM2A transfected lysate(37.20 KDa).
Lane 2: Non-transfected lysate.
Lane 1: EPM2A transfected lysate(37.20 KDa).
Lane 2: Non-transfected lysate.
Product Details
H00007957-D01P
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
EPM2A (AAH70047.1, 1 a.a. approximately 331 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
See Label
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Sequence of this protein is as follows: MRFRFGVVVP PAVAGARPEL LVVGSRPELG RWEPRGAVRL RPAGTAAGDG ALALQEPGLW LGEVELAAEE AAQDGAEPGR VDTFWYKFLK REPGGELSWE GNGPHHDRCC TYNENNLVDG VYCLPIGHWI EATGHTNEMK HTTDFYFNIA GHQAMHYSRI LPNIWLGSCP RQVEHVTIKL KHELGITAVM NFKTEWDIVQ NSSGCNRYPE PMTPDTMIKL YREEGLAYIW MPTPDMSTEG RVQMLPQAVC LLHALLEKGH IVYVHCNAGV GRSTAAVCGW LQYVMGWNLR KVQYFLMAKR PAVYIDEEAL ARAQEDFFQK FGKVRSSVCS L
Target Information
The Epilepsy, progressive myoclonus type 2A protein (EPM2A) is a dual-specificity phosphatase that associates with polyribosomes. Mutations in this gene have been associated with myoclonic epilepsy of Lafora. EPM2A interacts with a number of proteins known to be involved in glycogen metabolism and has been shown to have robust phosphatase activity against a phosphorylated complex carbohydrate, suggesting that EPM2A may be involved in the regulation of glycogen metabolism.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: epilepsy, progressive myoclonus type 2, Lafora disease (laforin); EPM2A; Glucan phosphatase; Glycogen phosphatase; Lafora PTPase; Laforin; LAFPTPase; RP1-28C20.2
Gene Aliases: EPM2; EPM2A; MELF
UniProt ID: (Human) O95278
Entrez Gene ID: (Human) 7957
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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