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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • EPS8 Antibodies

          Abnova

          EPS8 Polyclonal Antibody, MaxPab™

          View all (7) EPS8 antibodies

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          Cite EPS8 Polyclonal Antibody, MaxPab™

          • Antibody Testing Data (1)
          EPS8 Antibody in Western Blot (WB)
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          EPS8 Antibody in Western Blot (WB)
          Group 53 Created with Sketch.

          FIGURE: 1 / 1

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          EPS8 Antibody (H00002059-B01P) in WB

          EPS8 MaxPab polyclonal antibody. Western Blot analysis of EPS8 expression in K-562. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          EPS8 Antibody in Western Blot (WB)
          EPS8 Polyclonal Antibody, MaxPab™

          Product Details

          H00002059-B01P

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:1,000
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Mouse / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          EPS8 (NP_004438.3, 1 a.a. approximately 822 a.a) full-length human protein.
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          1 mg/mL

          Purification

          Protein A

          Storage buffer

          PBS, pH 7.4

          Contains

          no preservative

          Storage conditions

          -20°C, Avoid Freeze/Thaw Cycles

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          Product Specific Information

          Product may be used with Western Blot (Cell lysate).

          The Isotype of this product is composed of an IgG Mixture.

          Immunogen sequence: MNGHISNHPS SFGMYPSQMN GYGSSPTFSQ TDREHGSKTS AKALYEQRKN YARDSVSSVS DISQYRVEHL TTFVLDRKDA MITVDDGIRK LKLLDAKGKV WTQDMILQVD DRAVSLIDLE SKNELENFPL NTIQHCQAVM HSCSYDSVLA LVCKEPTQNK PDLHLFQCDE VKANLISEDI ESAISDSKGG KQKRRPDALR MISNADPSIP PPPRAPAPAP PGTVTQVDVR SRVAAWSAWA ADQGDFEKPR QYHEQEETPE MMAARIDRDV QILNHILDDI EFFITKLQKA AEAFSELSKR KKNKKGKRKG PGEGVLTLRA KPPPPDEFLD CFQKFKHGFN LLAKLKSHIQ NPSAADLVHF LFTPLNMVVQ ATGGPELASS VLSPLLNKDT IDFLNYTVNG DERQLWMSLG GTWMKARAEW PKEQFIPPYV PRFRNGWEPP MLNFMGATME QDLYQLAESV ANVAEHQRKQ EIKRLSTEHS SVSEYHPADG YAFSSNIYTR GSHLDQGEAA VAFKPTSNRH IDRNYEPLKT QPKKYAKSKY DFVARNNSEL SVLKDDILEI LDDRKQWWKV RNASGDSGFV PNNILDIVRP PESGLGRADP PYTHTIQKQR MEYGPRPADT PPAPSPPPTP APVPVPLPPS TPAPVPVSKV PANITRQNSS SSDSGGSIVR DSQRHKQLPV DRRKSQMEEV QDELIHRLTI GRSAAQKKFH VPRQNVPVIN ITYDSTPEDV KTWLQSKGFN PVTVNSLGVL NGAQLFSLNK DELRTVCPEG ARVYSQITVQ KAALEDSSGS SELQEIMRRR QEKISAAASD SGVESFDEGS SH

          Target Information

          This gene encodes a member of the EPS8 family. This protein contains one PH domain and one SH3 domain. It functions as part of the EGFR pathway, though its exact role has not been determined. Highly similar proteins in other organisms are involved in the transduction of signals from Ras to Rac and growth factor-mediated actin remodeling. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: Epidermal growth factor receptor kinase substrate 8

          View more View less

          Gene Aliases: DFNB102; EPS8

          View more View less

          UniProt ID: (Human) Q12929

          View more View less

          Entrez Gene ID: (Human) 2059

          View more View less

          Function(s)
          actin binding SH3/SH2 adaptor activity protein binding Rac GTPase binding scaffold/adaptor protein
          Process(es)
          signal transduction epidermal growth factor receptor signaling pathway cell proliferation adult locomotory behavior regulation of cell shape positive regulation of signal transduction exit from mitosis Rac protein signal transduction regulation of actin filament length actin cytoskeleton reorganization dendritic cell migration behavioral response to ethanol barbed-end actin filament capping actin filament bundle assembly actin crosslink formation actin polymerization-dependent cell motility
          It has to be done as per old AB suggested Products section.
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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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          We're here to help

          Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

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