Peptide sequence: QVDPRKYLDG DREKYLEDPA FDTNYSTEPC WQYSDHHENK YCDLECSHTC
Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 79%
ERK3 is a member of the Ser/Thr protein kinase family, and is most closely related to mitogen-activated protein kinases (MAP kinases). MAP kinases also known as extracellular signal-regulated kinases (ERKs), are activated through protein phosphorylation cascades and act as integration points for multiple biochemical signals. This kinase is localized in the nucleus, and has been reported to be activated in fibroblasts upon treatment with serum or phorbol esters.
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Protein Aliases: DKFZp686F03189; ERK-3; Erk-3 related; ERK3; Extracellular signal-regulated kinase 3; extracellular signal-regulated kinase, p97; HsT17250; MAP kinase 6; MAP kinase isoform p97; MAPK 6; mitogen activated protein kinase 4; mitogen activated protein kinase 6; Mitogen-activated protein kinase 6; p55-MAPK; p97-MAPK; p97MAPK; PRKM6; protein kinase, mitogen activated kinase 4; protein kinase, mitogen-activated 5; protein kinase, mitogen-activated 6
Gene Aliases: 2610021I23Rik; BOS_10992; D130053K17Rik; ERK3; HsT17250; Mapk4; MAPK6; Mapk63; p97MAPK; Prkm4; PRKM6; si:ch211-235f12.1