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Abnova
ESCO1 Polyclonal Antibody, MaxPab™
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FIGURE: 1 / 1
ESCO1 Antibody (H00114799-B01P) in WB
Western Blot analysis of ESCO1 expression in transfected 293T cell line (H00114799-T01) by ESCO1 MaxPab polyclonal antibody.
Lane 1: ESCO1 transfected lysate(18.92 KDa).
Lane 2: Non-transfected lysate.
Lane 1: ESCO1 transfected lysate(18.92 KDa).
Lane 2: Non-transfected lysate.
Product Details
H00114799-B01P
Product Specifications
Host/Isotype
Mouse
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
ESCO1 (AAH36943.1, 1 a.a. approximately 172 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
See Label
Amount
50 µg
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Sequence of this protein is as follows: MVLPEDPKYA LKKVDEIREM VDNDLGFQQA PLMCYSRTKT LLFISNDKKV VGCLIAEHIQ WGYRVIEEKL PVIRSEEEKV RFERQKAWCC STLPEPAICG ISRIWVFSMM RRKKIASRMI ECLRSNFIYG SYLSKEEIAF SDPTPDGKLF ATQYCGTGQF LVYNFINGQN ST
Target Information
EFO1 (Establishment factor-like protein 1), also known as ESCO1 (establishment of cohesion 1 homolog1) or ESO1, is a member of the acetyltransferase family (GCN5 subfamily). It is a ubiquitously expressed nuclear protein that plays an important role in sister chromatid cohesion. At its C-terminus, EFO1 contains an H2C2 zinc finger motif and an acetyltransferase domain that exhibits acetyltransferase activity in vivo. Its N-terminus, containing two domains that are similar o alpha- and beta-type linker histone proteins, is essential for EFO1 association with chromosomes. EFO1 is responsible for coupling cohesion and DNA replication processes thereby ensuring proper pairing of sister chromatids. EFO1 is phosphorylated during mitosis and this may act to regulate EFO1 activity. Due to alternative splicing events, three EFO1 isoforms exist.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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