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Invitrogen
ETFDH Polyclonal Antibody
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FIGURE: 1 / 4
ETFDH Antibody (PA5-100143) in ICC/IF
Immunofluorescent analysis of ETFDH in HeLa cells. Samples were fixed with paraformaldehyde, permeabilized with 0.1% Triton X-100, blocked with 10% serum (45 min at 25°C) incubated with ETFDH polyclonal antibody (Product # PA5-100143) using a dilution of 1:200 (1 hr, 37°C), and followed by goat anti-rabbit IgG Alexa Fluor 594 at a dilution of 1:600.
Product Details
PA5-100143
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human ETFDH(Accession Q16134), corresponding to amino acid residues N528-R578.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total ETFDH.
Target Information
Electron-transferring-flavoprotein dehydrogenase in the inner mitochondrial membrane accepts electrons from electron-transfer flavoprotein which is located in the mitochondrial matrix and reduces ubiquinone in the mitochondrial membrane. The protein is synthesized as a 67-kDa precursor which is targeted to mitochondria and processed in a single step to a 64-kDa mature form located in the mitochondrial membrane. Deficiency in electron-transferring-flavoprotein dehydrogenase have been demonstrated in some patients with type II glutaricacidemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial; electron transferring flavoprotein dehydrogenase; Electron-transferring-flavoprotein dehydrogenase; ETF dehydrogenase; ETF-QO; ETF-ubiquinone oxidoreductase
Gene Aliases: 0610010I20Rik; AV001013; ETFDH; ETFQO; MADD
UniProt ID: (Human) Q16134, (Mouse) Q921G7
Entrez Gene ID: (Human) 2110, (Rat) 295143, (Mouse) 66841
electron-transferring-flavoprotein dehydrogenase activity
electron carrier activity
oxidoreductase activity
oxidoreductase activity, oxidizing metal ions with flavin as acceptor
metal ion binding
quinone binding
ubiquinone binding
flavin adenine dinucleotide binding
4 iron, 4 sulfur cluster binding
iron-sulfur cluster binding
oxidoreductase
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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