|Tested species reactivity||Human|
|Published species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 496 and 885 of Human EXOSC10|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 10% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Miscellaneous PubMed (MISC)||See 1 publications below|
PA5-28672 targets EXOSC10 in IHC (P), IP and WB applications and shows reactivity with Human samples.
The PA5-28672 immunogen is recombinant fragment corresponding to a region within amino acids 496 and 885 of Human EXOSC10.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Inhibition of telomerase RNA decay rescues telomerase deficiency caused by dyskerin or PARN defects.
PA5-28672 was used in western blot to identify the enzymes and mechanisms responsible for human telomerase RNA degradation
|Shukla S,Schmidt JC,Goldfarb KC,Cech TR,Parker R||Nature structural and molecular biology (23:286)||2016|