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Proteintech
EXOSC8 Polyclonal Antibody
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Product Details
11979-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
EXOSC8 Fusion Protein Ag2605 (1-276 aa encoded by BC020773)
Conjugate
Form
Liquid
Concentration
0.24 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MAAGFKTVE PLEYYRRFLK ENCRPDGREL GEFRTTTVNI GSISTADGSA LVKLGNTTVI CGVKAEFAAP STDAPDKGYV VPNVDLPPLC SSRFRSGPPG EEAQVASQFI ADVIENSQII QKEDLCISPG KLVWVLYCDL ICLDYDGNIL DACTFALLAA LKNVQLPEVT INEETALAEV NLKKKSYLNI RTHPVATSFA VFDDTLLIVD PTGEEEHLAT GTLTIVMDEE GKLCCLHKPG GSGLTGAKLQ DCMSRAVTRH KEVKKLMDEV IKSMKPK (1-276 aa encoded by BC020773)
Target Information
This gene encodes a 3'-5' exoribonuclease that specifically interacts with mRNAs containing AU-rich elements. The encoded protein is part of the exosome complex that is important for the degradation of numerous RNA species. A pseudogene of this gene is found on chromosome 6.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: CBP-interacting protein 3; Exosome complex component RRP43; exosome complex exonuclease RRP43; Exosome component 8; OIP-2; Opa interacting protein 2; Opa-interacting protein 2; p9; Ribosomal RNA-processing protein 43; RP11-421P11.3
Gene Aliases: 2310032N20Rik; bA421P11.3; CIP3; EAP2; EXOSC8; mKIAA4013; OIP2; p9; PCH1C; RRP43; Rrp43p
UniProt ID: (Human) Q96B26, (Mouse) Q9D753
Entrez Gene ID: (Human) 11340, (Mouse) 69639, (Rat) 295050
exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
rRNA processing
biological_process
nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'
U1 snRNA 3'-end processing
U4 snRNA 3'-end processing
U5 snRNA 3'-end processing
regulation of mRNA stability
exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay
nuclear mRNA surveillance
nuclear polyadenylation-dependent rRNA catabolic process
nuclear polyadenylation-dependent tRNA catabolic process
nuclear polyadenylation-dependent mRNA catabolic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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