Recommended positive controls: A549, HeLa, HepG2, HCT116, Jurkat, Raji, NCI-H929.
Predicted reactivity: Mouse (91%), Rhesus Monkey (99%), Bovine (93%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
This gene encodes a 3'-5' exoribonuclease that specifically interacts with mRNAs containing AU-rich elements. The encoded protein is part of the exosome complex that is important for the degradation of numerous RNA species. A pseudogene of this gene is found on chromosome 6.
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Protein Aliases: CBP-interacting protein 3; Exosome complex component RRP43; exosome complex exonuclease RRP43; Exosome component 8; OIP-2; Opa interacting protein 2; Opa-interacting protein 2; p9; Ribosomal RNA-processing protein 43; RP11-421P11.3
Gene Aliases: bA421P11.3; CIP3; EAP2; EXOSC8; OIP2; p9; PCH1C; RRP43; Rrp43p
UniProt ID: (Human) Q96B26
Entrez Gene ID: (Human) 11340