PA5-27173 targets Endothelin B Receptor in Western Blot and Immunohistochemistry - Paraffin applications and shows reactivity with Human, mouse and Rat samples.
The PA5-27173 immunogen is a synthetic peptide corresponding to a region within amino acids 8 and 111 of Endothelin B Receptor.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
Non-specific receptor for endothelin 1, 2, and 3. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
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Protein Aliases: Ednra; endothelin B receptor; Endothelin receptor non-selective type; endothelin receptor subtype B1; Endothelin receptor type B; endothelin-B receptor; ET-B; ET-BR; Etb; piebald
Gene Aliases: ABCDS; Ednra; EDNRB; ET-B; ET-BR; ETB; ETB1; ETBR; ETR-b; ETRB; HSCR; HSCR2; Sox10m1; WS4A