Invitrogen

Endothelin B Receptor Polyclonal Antibody

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Endothelin B Receptor Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemical analysis of Endothelin B Receptor in the membrane of paraffin-embedded U87 xenograft using an Endothelin B Receptor polyclonal antibody (Product # PA5-27173) at a dilution of 1:500.

Endothelin B Receptor Antibody in Western Blot (WB) — Western blot analysis of Endothelin B Receptor using 50 µg of mouse brain lysate. Samples were loaded onto a 10% SDS-PAGE gel and probed with an Endothelin B Receptor polyclonal antibody (Product # PA5-27173) at a dilution of 1:3000.

Product Details

Tested Applications

Dilution

Immunohistochemistry (Paraffin) (IHC (P))

1:100-1:1000

Western Blot (WB)

1:500-1:3000

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host / Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide corresponding to a region within amino acids 8 and 111 of Endothelin B Receptor

Conjugate

Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7, with 50% glycerol

Contains

0.01% thimerosal

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

RRID

AB_2544649

Product Specific Information

PA5-27173 targets Endothelin B Receptor in Western Blot and Immunohistochemistry - Paraffin applications and shows reactivity with Human, mouse and Rat samples.

The PA5-27173 immunogen is a synthetic peptide corresponding to a region within amino acids 8 and 111 of Endothelin B Receptor.

Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

Target Information

Non-specific receptor for endothelin 1, 2, and 3. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: Ednra; endothelin B receptor; Endothelin receptor non-selective type; endothelin receptor subtype B1; Endothelin receptor type B; endothelin-B receptor; ET-B; ET-BR; Etb; piebald

Gene Aliases: ABCDS; Ednra; EDNRB; ET-B; ET-BR; ETB; ETB1; ETBR; ETR-b; ETRB; HSCR; HSCR2; Sox10m1; WS4A

UniProt ID: (Human) P24530, (Rat) P21451, (Mouse) P48302

Entrez Gene ID: (Human) 1910, (Rat) 50672, (Mouse) 13618

Molecular Function: G-protein coupled receptor receptor