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Enolase Polyclonal Antibody
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Product Details
OSN00063W-100UL
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Non-human primate,
Rat
Host/Isotype
Rabbit
/ Ig
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide from aa region 200-280 of internal region of human Enolase conjugated to blue carrier protein was used as the antigen
Conjugate
Form
Lyophilized
Concentration
Conc. Not Determined
Storage buffer
whole serum
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
The peptide is homologous in rat and mouse.
Specificity of this antibody: Enolase (alpha, beta, gamma).
Target Information
Enolase 1 is a multifunctional enzyme that, as well as its role in glycolysis, plays a part in various processes such as growth control, hypoxia tolerance and allergic responses. May also function in the intravascular and pericellular fibrinolytic system due to its ability to serve as a receptor and activator of plasminogen on the cell surface of several cell-types such as leukocytes and neurons. Stimulates immunoglobulin production.MBP1 binds to the myc promoter and acts as a transcriptional repressor. May be a tumor suppressor.Enolase 2 has neurotrophic and neuroprotective properties on a broad spectrum of central nervous system (CNS) neurons. Binds, in a calcium-dependent manner, to cultured neocortical neurons and promotes cell survival.Enolase 3 appears to have a function in striated muscle development and regeneration.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 2-phospho-D-glycerate hydro-lyase; 2-phospho-D-glycerate hydrolase; 2-phospho-D-glycerate hydrolyase; alpha enolase; alpha enolase (EC 4.2.1.11); alpha enolase like 1; Alpha-enolase; Beta-enolase; c-Myc promoter binding protein; C-myc promoter-binding protein; ENO1 intronic transcript 1; ENO1 intronic transcript 1 (non-protein coding); ENO2; Enolase 1; enolase 1, (alpha); enolase 1, alpha non-neuron; Enolase 2; enolase 2 (gamma, neuronal); Enolase 3; enolase 3 (beta, muscle); enolase-alpha; epididymis secretory protein Li 17; epididymis secretory protein Li 279; gamma enolase; Gamma-enolase; MBP-1; MPB-1; MSE; muscle enriched enolase; Muscle specific enolase (beta beta enolose) (two splicing products); Muscle-specific enolase; MYC promoter-binding protein 1; Neural enolase; neuron specific gamma enolase; Neuron-specific enolase; neuronal enriched enolase; neurone-specific enolase; NNE; Non-neural enolase; NSE; Phosphopyruvate hydratase; Plasminogen-binding protein; Skeletal muscle enolase; tau-crystallin; transcription factor; unnamed protein product
Gene Aliases: 0610008I15; AI837106; AL022784; BBE; D6Ertd375e; Eno-1; Eno-2; Eno-3; ENO1; ENO1-IT1; ENO1L1; ENO2; ENO3; GSD13; HEL-S-17; HEL-S-279; MBP-1; MBPB1; MPB1; MSE; NNE; NSE; PPH; RNEN3
UniProt ID: (Human) P06733, (Human) P09104, (Human) P13929, (Mouse) P17182, (Rat) P04764, (Mouse) P17183, (Rat) P07323, (Mouse) P21550, (Rat) P15429
Entrez Gene ID: (Human) 2023, (Human) 2026, (Human) 2027, (Mouse) 13806, (Rat) 24333, (Mouse) 13807, (Rat) 24334, (Mouse) 13808, (Rat) 25438
magnesium ion binding
RNA polymerase II regulatory region sequence-specific DNA binding
transcription corepressor binding
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
transcription corepressor activity
RNA binding
phosphopyruvate hydratase activity
protein binding
lyase activity
protein homodimerization activity
cadherin binding
metal ion binding
GTPase binding
enzyme binding
identical protein binding
macromolecular complex binding
poly(A) RNA binding
protein heterodimerization activity
lyase
negative regulation of transcription from RNA polymerase II promoter
gluconeogenesis
glycolytic process
response to virus
positive regulation of plasminogen activation
negative regulation of cell growth
negative regulation of transcription, DNA-templated
positive regulation of muscle contraction
canonical glycolysis
negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway
positive regulation of ATP biosynthetic process
response to xenobiotic stimulus
response to estradiol
in utero embryonic development
positive regulation of binding
cellular response to acid chemical
response to organic cyclic compound
response to drug
aging
substantia nigra development
skeletal muscle tissue regeneration
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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