Product References
Value of Immunohistochemical Expression of Apelin, Succinate Dehydrogenase B, Chromogranin B, Human Epidermal Growth Factor Receptor-2, Contactin 4, and Succinyl-CoA Synthetase Subunit Beta in Differentiating Metastatic From Non-Metastatic Pheochromocytoma and Paraganglioma.
Frontiers in endocrinology
Wang Y,Chen D,Pang Y,Xu X,Guan X,Liu L
MA5-14057 was used in Immunohistochemistry to observe and quantify the expression of apelin, SDHB, CHGB, ERBB-2, CNTN4, and SUCLG2 in paraffin-embedded samples from a total of 369 patients with pathologically and surgically confirmed PPGLs at Xiangya Hospital, Central South University, between June 2010 and June 2020.
Thu May 19 00:00:00 EDT 2022
Value of Immunohistochemical Expression of Apelin, Succinate Dehydrogenase B, Chromogranin B, Human Epidermal Growth Factor Receptor-2, Contactin 4, and Succinyl-CoA Synthetase Subunit Beta in Differentiating Metastatic From Non-Metastatic Pheochromocytoma and Paraganglioma.
Frontiers in endocrinology
Wang Y,Chen D,Pang Y,Xu X,Guan X,Liu L
MA5-14057 was used in Immunohistochemistry to observe and quantify the expression of apelin, SDHB, CHGB, ERBB-2, CNTN4, and SUCLG2 in paraffin-embedded samples from a total of 369 patients with pathologically and surgically confirmed PPGLs at Xiangya Hospital, Central South University, between June 2010 and June 2020.
Thu May 19 00:00:00 EDT 2022
Helicobacter pylori infection impairs chaperone-assisted maturation of Na-K-ATPase in gastric epithelium.
American journal of physiology. Gastrointestinal and liver physiology
Marcus EA,Tokhtaeva E,Jimenez JL,Wen Y,Naini BV,Heard AN,Kim S,Capri J,Cohn W,Whitelegge JP,Vagin O
MA5-14057 was used in Western Blot to provide evidence that Helicobacter pylori decreases levels of Na-K-ATPase, a vital transport enzyme, in gastric epithelia, which contributes to H. pylori-induced gastric injury.
Fri May 01 00:00:00 EDT 2020
Repurposing of KLF5 activates a cell cycle signature during the progression from a precursor state to oesophageal adenocarcinoma.
eLife
Rogerson C,Ogden S,Britton E,Ang Y,Sharrocks AD
Published figure using ErbB2 (HER-2) cocktail antibody (Product # MA5-14057) in Western Blot
Thu Sep 03 00:00:00 EDT 2020
Repurposing of KLF5 activates a cell cycle signature during the progression from a precursor state to oesophageal adenocarcinoma.
eLife
Rogerson C,Ogden S,Britton E,Ang Y,Sharrocks AD
Published figure using ErbB2 (HER-2) cocktail antibody (Product # MA5-14057) in Western Blot
Thu Sep 03 00:00:00 EDT 2020
Proteomic Profile of Sorafenib Resistance in Hepatocellular Carcinoma; GRP78 Expression Is Associated With Inferior Response to Sorafenib.
Cancer genomics & proteomics
Feng YH,Tung CL,Su YC,Tsao CJ,Wu TF
MA5-14057 was used in Immunohistochemistry to study GRP78 as a biomarker for Sorafenib resistance in treating hepatocellular carcinoma.
Wed Mar 11 00:00:00 EDT 2020
Proteomic Profile of Sorafenib Resistance in Hepatocellular Carcinoma; GRP78 Expression Is Associated With Inferior Response to Sorafenib.
Cancer genomics & proteomics
Feng YH,Tung CL,Su YC,Tsao CJ,Wu TF
MA5-14057 was used in Immunohistochemistry to study GRP78 as a biomarker for Sorafenib resistance in treating hepatocellular carcinoma.
Wed Mar 11 00:00:00 EDT 2020
Differential effect of parity on rat mammary carcinogenesis after pre- or post-pubertal exposure to radiation.
Scientific reports
Takabatake M,Daino K,Imaoka T,Blyth BJ,Kokubo T,Nishimura Y,Showler K,Hosoki A,Moriyama H,Nishimura M,Kakinuma S,Fukushi M,Shimada Y
MA5-14057 was used in Immunohistochemistry to show parity protects against radiation-induced rat mammary carcinogenesis depending on the age at exposure; the mechanisms may involve changes in hormone levels and cancer tissue.
Tue Sep 25 00:00:00 EDT 2018
Activating ERBB4 mutations in non-small cell lung cancer.
Oncogene
Kurppa KJ,Denessiouk K,Johnson MS,Elenius K
MA5-14057 was used in immunoprecipitation to characterize nine mutations in the receptor tyrosine kinase ERBB4 identified in lung adenocarcinoma
Thu Mar 10 00:00:00 EST 2016
Runx2 Expression as a Potential Prognostic Marker in Invasive Ductal Breast Carcinoma.
Pathology oncology research : POR
El-Gendi SM,Mostafa MF
MA5-14057 was used in immunohistochemistry - paraffin section to elucidate the role of Runx2 during the early stages of breast cancer and metastasis
Fri Jul 01 00:00:00 EDT 2016
HER2-HER3 dimer quantification by FLIM-FRET predicts breast cancer metastatic relapse independently of HER2 IHC status.
Oncotarget
Weitsman G,Barber PR,Nguyen LK,Lawler K,Patel G,Woodman N,Kelleher MT,Pinder SE,Rowley M,Ellis PA,Purushotham AD,Coolen AC,Kholodenko BN,Vojnovic B,Gillett C,Ng T
MA514057 was used in immunocytochemistry and immunohistochemistry to assess the use of HER2-HER3 dimerization as a biomarker for breast cancer
Tue Aug 09 00:00:00 EDT 2016
Robust Bayesian Fluorescence Lifetime Estimation, Decay Model Selection and Instrument Response Determination for Low-Intensity FLIM Imaging.
PloS one
Rowley MI,Coolen AC,Vojnovic B,Barber PR
MA514057 was used in immunohistochemistry to investigate Bayesian methods for the analysis of exponential decay data
Wed Jul 19 00:00:00 EDT 2017
A genetic basis for the variation in the vulnerability of cancer to DNA damage.
Nature communications
Yard BD,Adams DJ,Chie EK,Tamayo P,Battaglia JS,Gopal P,Rogacki K,Pearson BE,Phillips J,Raymond DP,Pennell NA,Almeida F,Cheah JH,Clemons PA,Shamji A,Peacock CD,Schreiber SL,Hammerman PS,Abazeed ME
MA514057 was used in western blot to identify genetic features regulating cell survival after exposure to radiation.
Mon Apr 25 00:00:00 EDT 2016
Gemcitabine treatment enhances HER2 expression in low HER2-expressing breast cancer cells and enhances the antitumor effects of trastuzumab emtansine.
Oncology reports
Kan S,Koido S,Okamoto M,Hayashi K,Ito M,Kamata Y,Komita H,Ishidao T,Nagasaki E,Homma S
MA5-14057 was used in western blot to report that gemcitabine treatment increases HER2 expression by low HER2-expressing breast cancer cells
Wed Jul 01 00:00:00 EDT 2015
Discordances in HER2 status between primary gastric cancer and corresponding metastatic sites.
Japanese journal of clinical oncology
Gumusay O,Benekli M,Ekinci O,Baykara M,Ozet A,Coskun U,Demirci U,Uner A,Dursun A,Atak EY,Buyukberber S
MA5-14057 was used in immunohistochemistry - paraffin section to determine the rate of human epidermal growth factor receptor-2 discordance and its effect on treatment decisions in patients with advanced gastric cancer.
Fri May 01 00:00:00 EDT 2015
Expression of PAM50 Genes in Lung Cancer: Evidence that Interactions between Hormone Receptors and HER2/HER3 Contribute to Poor Outcome.
Neoplasia (New York, N.Y.)
Siegfried JM,Lin Y,Diergaarde B,Lin HM,Dacic S,Pennathur A,Weissfeld JL,Romkes M,Nukui T,Stabile LP
MA5-14057 was used in immunohistochemistry - paraffin section to assess non-small cell lung cancers using a breast cancer-risk predictor gene signature
Sun Nov 01 00:00:00 EDT 2015
Molecular architecture of the ErbB2 extracellular domain homodimer.
Oncotarget
Hu S,Sun Y,Meng Y,Wang X,Yang W,Fu W,Guo H,Qian W,Hou S,Li B,Rao Z,Lou Z,Guo Y
MA5-14057 was used in immunoprecipitation and western blot to elucidate the dimerization of ErbB2
Fri Jan 30 00:00:00 EST 2015
The chemomodulatory effects of resveratrol and didox on herceptin cytotoxicity in breast cancer cell lines.
Scientific reports
Abdel-Latif GA,Al-Abd AM,Tadros MG,Al-Abbasi FA,Khalifa AE,Abdel-Naim AB
MA5-14057 was used in immunocytochemistry to study breast cancer cell lines and chemomodulatory effects of didox and resveratrol on herceptin cytotoxicity
Thu Jul 09 00:00:00 EDT 2015
Up-regulation of HER2 by gemcitabine enhances the antitumor effect of combined gemcitabine and trastuzumab emtansine treatment on pancreatic ductal adenocarcinoma cells.
BMC cancer
Kan S,Koido S,Okamoto M,Hayashi K,Ito M,Kamata Y,Komita H,Nagasaki E,Homma S
MA5-14057 was used in western blot to discuss how to improve treatment of pancreatic ductal adenocarcinomas with trastuzumab emtansine
Fri Oct 16 00:00:00 EDT 2015
Client Proteins and Small Molecule Inhibitors Display Distinct Binding Preferences for Constitutive and Stress-Induced HSP90 Isoforms and Their Conformationally Restricted Mutants.
PloS one
Prince TL,Kijima T,Tatokoro M,Lee S,Tsutsumi S,Yim K,Rivas C,Alarcon S,Schwartz H,Khamit-Kush K,Scroggins BT,Beebe K,Trepel JB,Neckers L
MA5-14057 was used in western blot to characterize distinct binding preferences for constitutive and stress-induced HSP90 isoforms and conformationally restricted mutants in regards to client proteins and small molecule inhibitors
Fri Jun 17 00:00:00 EDT 2016
Proteomic screening identifies a YAP-driven signaling network linked to tumor cell proliferation in human schwannomas.
Neuro-oncology
Boin A,Couvelard A,Couderc C,Brito I,Filipescu D,Kalamarides M,Bedossa P,De Koning L,Danelsky C,Dubois T,Hupé P,Louvard D,Lallemand D
MA5-14057 was used in immunohistochemistry - paraffin section to investigate the expression and activity of receptor tyrosine kinases, MAP kinase, AKT, or Hippo pathways in human schwannomas
Mon Sep 01 00:00:00 EDT 2014
T47D breast cancer cells switch from ER/HER to HER/c-Src signaling upon acquiring resistance to the antiestrogen fulvestrant.
Cancer letters
Kirkegaard T,Hansen SK,Larsen SL,Reiter BE,Sørensen BS,Lykkesfeldt AE
MA5-14057 was used in immunoprecipitation to study the switch from ER/HER to HER/c-Src signaling as T47D breast cancer cells acquire fulvestrant resistance
Sat Mar 01 00:00:00 EST 2014
HER2/neu in Endometrial Cancer: A Promising Therapeutic Target With Diagnostic Challenges.
Archives of pathology & laboratory medicine
Buza N,Roque DM,Santin AD
MA5-14057 was used in immunohistochemistry to present a review of literature data on the therapeutic potential of HER2/neu in endometrial carcinoma
Sat Mar 01 00:00:00 EST 2014
Soluble-E-cadherin activates HER and IAP family members in HER2+ and TNBC human breast cancers.
Molecular carcinogenesis
Brouxhon SM,Kyrkanides S,Teng X,O'Banion MK,Clarke R,Byers S,Ma L
MA5-14057 was used in immunohistochemistry to study targeting sEcad for treatment of breast cancer
Sat Nov 01 00:00:00 EDT 2014
Neuregulin-1/glial growth factor stimulates Schwann cell migration by inducing α5 β1 integrin-ErbB2-focal adhesion kinase complex formation.
Genes to cells : devoted to molecular & cellular mechanisms
Wakatsuki S,Araki T,Sehara-Fujisawa A
MA5-14057 was used in immunohistochemistry, immunoprecipitation, and western blot to study the role of neuregulin-1/glial growth factor in Schwann cell migration and its mechanism
Wed Jan 01 00:00:00 EST 2014
Flotillin depletion affects ErbB protein levels in different human breast cancer cells.
Biochimica et biophysica acta
Asp N,Pust S,Sandvig K
MA5-14057 was used in immunoprecipitation and western blot to study the role of flotillin in the oncogenic effect of ErbB
Mon Sep 01 00:00:00 EDT 2014
Monitoring afatinib treatment in HER2-positive gastric cancer with 18F-FDG and 89Zr-trastuzumab PET.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine
Janjigian YY,Viola-Villegas N,Holland JP,Divilov V,Carlin SD,Gomes-DaGama EM,Chiosis G,Carbonetti G,de Stanchina E,Lewis JS
MA5-14057 was used in western blot to study the pharmacodynamics of afatinib in HER2-positive gastric cancer using PET
Sat Jun 01 00:00:00 EDT 2013
Evaluation of the antitumor activity of dacomitinib in models of human bladder cancer.
Molecular medicine (Cambridge, Mass.)
Grivas PD,Day KC,Karatsinides A,Paul A,Shakir N,Owainati I,Liebert M,Kunju LP,Thomas D,Hussain M,Day ML
MA5-14057 was used in immunohistochemistry and western blot to study the efficacy and tolerability of the irreversible tyrosine kinase inhibitor dacomitinib in human bladder cancer models
Fri Nov 08 00:00:00 EST 2013
HER2/neu expression correlates with vasculogenic mimicry in invasive breast carcinoma.
Journal of cellular and molecular medicine
Liu T,Sun B,Zhao X,Gu Q,Dong X,Yao Z,Zhao N,Chi J,Liu N,Sun R,Ma Y
MA5-14057 was used in western blot to study the role of HER2/neu in vasculogenic mimicry in invasive breast carcinoma
Tue Jan 01 00:00:00 EST 2013
A cell-based screening system for influenza A viral RNA transcription/replication inhibitors.
Scientific reports
Ozawa M,Shimojima M,Goto H,Watanabe S,Hatta Y,Kiso M,Furuta Y,Horimoto T,Peters NR,Hoffmann FM,Kawaoka Y
MA5-14057 was used in western blot to develop a cell-based screening system to identify compounds that inhibit influenza A viral RNA transcription/replication
Mon Sep 30 00:00:00 EDT 2013
Hormone receptors and age distribution in breast cancer patients at a university hospital in northern egypt.
Breast cancer : basic and clinical research
Hussein O,Mosbah M,Farouk O,Farag K,El-Saed A,Arafa M,Abdallah A
MA5-14057 was used in immunohistochemistry to study whether there is a relationship between hormone receptor status, age profile, and clinicopathology in northern Egyptian breast cancer patients
Fri Jul 05 00:00:00 EDT 2013
Circulating tumor cells in immunohistochemical subtypes of metastatic breast cancer: lack of prediction in HER2-positive disease treated with targeted therapy.
Annals of oncology : official journal of the European Society for Medical Oncology
Giordano A,Giuliano M,De Laurentiis M,Arpino G,Jackson S,Handy BC,Ueno NT,Andreopoulou E,Alvarez RH,Valero V,De Placido S,Hortobagyi GN,Reuben JM,Cristofanilli M
MA5-14057 was used in immunohistochemistry to study the predictive value of circulating tumor cells in subtypes of metastatic breast cancer
Tue May 01 00:00:00 EDT 2012
Clinically used breast cancer markers such as estrogen receptor, progesterone receptor, and human epidermal growth factor receptor 2 are unstable throughout tumor progression.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology
Lindström LS,Karlsson E,Wilking UM,Johansson U,Hartman J,Lidbrink EK,Hatschek T,Skoog L,Bergh J
MA5-14057 was used in immunocytochemistry and immunohistochemistry to study the stability of clinical biomarkers of breast cancer as the tumor progresses and the implications for patient management
Fri Jul 20 00:00:00 EDT 2012
HER2-associated radioresistance of breast cancer stem cells isolated from HER2-negative breast cancer cells.
Clinical cancer research : an official journal of the American Association for Cancer Research
Duru N,Fan M,Candas D,Menaa C,Liu HC,Nantajit D,Wen Y,Xiao K,Eldridge A,Chromy BA,Li S,Spitz DR,Lam KS,Wicha MS,Li JJ
MA5-14057 was used in western blot to isolate and characterize radiation-resistant HER2-positive breast cancer stem cells isolated from HER2-negative breast cancer cells subjected to radiation treatment
Sat Dec 15 00:00:00 EST 2012
Optical imaging with her2-targeted affibody molecules can monitor hsp90 treatment response in a breast cancer xenograft mouse model.
Clinical cancer research : an official journal of the American Association for Cancer Research
van de Ven SM,Elias SG,Chan CT,Miao Z,Cheng Z,De A,Gambhir SS
MA5-14057 was used in western blot to study the suitability of optical imaging using Her2-targeted affibodies as a methodology for monitoring the responses of breast cancer xenograft models to Hsp90 inhibitors
Wed Feb 15 00:00:00 EST 2012
An in vivo model of epithelial to mesenchymal transition reveals a mitogenic switch.
Cancer letters
Jahn SC,Law ME,Corsino PE,Parker NN,Pham K,Davis BJ,Lu J,Law BK
MA5-14057 was used in western blot to study mitogenic signaling changes during the epithelial-mesenchymal transition in an in vivo model
Sun Dec 30 00:00:00 EST 2012
ABCB1/MDR1 contributes to the anticancer drug-resistant phenotype of IPH-926 human lobular breast cancer cells.
Cancer letters
Krech T,Scheuerer E,Geffers R,Kreipe H,Lehmann U,Christgen M
MA5-14057 was used in western blot to study the role of the ABCB1/MDR1 transporter in mediating human lobular breast cancer cell drug resistance
Tue Feb 28 00:00:00 EST 2012
Trastuzumab (herceptin) targets gastric cancer stem cells characterized by CD90 phenotype.
Oncogene
Jiang J,Zhang Y,Chuai S,Wang Z,Zheng D,Xu F,Zhang Y,Li C,Liang Y,Chen Z
MA5-14057 was used in western blot to investigate the role of CD90+ cancer stem cells in gastric tumorigenesis and its therapeutic implications
Thu Feb 09 00:00:00 EST 2012
Strong EGFR signaling in cell line models of ERBB2-amplified breast cancer attenuates response towards ERBB2-targeting drugs.
Oncogenesis
Henjes F,Bender C,von der Heyde S,Braun L,Mannsperger HA,Schmidt C,Wiemann S,Hasmann M,Aulmann S,Beissbarth T,Korf U
MA5-14057 was used in immunohistochemistry to investigate the role of EGFR signaling in the effects of ERBB2-targeting drugs
Mon Jul 02 00:00:00 EDT 2012
HER2/neu gene amplification and protein overexpression in gastric and gastroesophageal junction adenocarcinoma: a review of histopathology, diagnostic testing, and clinical implications.
Archives of pathology & laboratory medicine
Hechtman JF,Polydorides AD
MA5-14057 was used in immunohistochemistry to review the literature on HER2/neu gene amplification and protein overexpression in gastric and gastroesophageal junction adenocarcinoma
Fri Jun 01 00:00:00 EDT 2012
Quantitative DNA methylation and recurrence of breast cancer: a study of 30 candidate genes.
Cancer biomarkers : section A of Disease markers
Cheol Kim D,Thorat MA,Lee MR,Cho SH,Vasiljević N,Scibior-Bentkowska D,Wu K,Ahmad AS,Duffy S,Cuzick JM,Lorincz AT
MA5-14057 was used in immunohistochemistry to study the value of quantifying the DNA methylation status of a panel of genes for predicting breast cancer recurrence
Thu Feb 28 00:00:00 EST 2013
C-Erb-b2 oncogene expression in intraductal proliferative lesions of the breast.
Bosnian journal of basic medical sciences
Eren F,Calay Z,Durak H,Eren B,Comunoğlu N,Aydin O
MA5-14057 was used in immunohistochemistry to study the diagnostic and prognostic value of C-Erb-b2 expression in intraductal proliferative lesions of the breast
Wed Feb 01 00:00:00 EST 2012
Prognostic value of oncoprotein expressions in thyroid papillary carcinoma.
Medical oncology (Northwood, London, England)
Balta AZ,Filiz AI,Kurt Y,Sucullu I,Yucel E,Akin ML
MA5-14057 was used in immunohistochemistry to identify the relationship between oncoprotein expression and clinical symptoms of carcinoma
Fri Jun 01 00:00:00 EDT 2012
Clinicopathologic features of the mixed epithelial and mesenchymal type metaplastic breast carcinoma with myoepithelial differentiation in a subset of six cases.
Pathology, research and practice
Yigit S,Pehlivan FS,Evcim G,Etit D
MA5-14057 was used in immunohistochemistry to study six cases of mixed epithelial and mesenchymal type metaplastic breast carcinoma with myoepithelial differentiation
Thu Mar 15 00:00:00 EDT 2012
Stromal caveolin-1 expression in breast carcinoma. Correlation with early tumor recurrence and clinical outcome.
Pathology oncology research : POR
El-Gendi SM,Mostafa MF,El-Gendi AM
MA5-14057 was used in immunohistochemistry to study the prognostic value of stromal caveolin-1 in breast cancer
Sun Apr 01 00:00:00 EDT 2012
Early changes in carcinogenesis of colorectal adenomas.
The West Indian medical journal
Toru S,Bilezikçi B
MA5-14057 was used in immunohistochemistry to study early changes and high risk factors in carcinogenesis of colorectal adenomas
Sun Jan 01 00:00:00 EST 2012
Association of human epidermal growth factor receptor-2 expression and clinicopathological findings in patients with colorectal cancer.
Asian Pacific journal of cancer prevention : APJCP
Karaca H,Deniz K,Berk V,Inanc M,Ozkan M
MA5-14057 was used in immunohistochemistry to study the relationship between HER2 expression and clinocopathological features in patients with colorectal cancer
Sat Apr 23 00:00:00 EDT 2016
Reorienting the Fab domains of trastuzumab results in potent HER2 activators.
PloS one
Scheer JM,Sandoval W,Elliott JM,Shao L,Luis E,Lewin-Koh SC,Schaefer G,Vandlen R
MA5-14057 was used in western blot to study the conversion of trastuzumab into a potent HER2 activator via geometric reorientation of the Fab domains
Mon Jun 17 00:00:00 EDT 2013
Invasive lobular carcinoma with extracellular mucin as a distinct variant of lobular carcinoma: a case report.
Diagnostic pathology
Haltas H,Bayrak R,Yenidunya S,Kosehan D,Sen M,Akin K
MA5-14057 was used in immunohistochemistry to report on a case of invasive lobular carcinoma with extracellular mucin
Mon Aug 06 00:00:00 EDT 2012
Antitumor activity of SNX-2112, a synthetic heat shock protein-90 inhibitor, in MET-amplified tumor cells with or without resistance to selective MET Inhibition.
Clinical cancer research : an official journal of the American Association for Cancer Research
Bachleitner-Hofmann T,Sun MY,Chen CT,Liska D,Zeng Z,Viale A,Olshen AB,Mittlboeck M,Christensen JG,Rosen N,Solit DB,Weiser MR
MA5-14057 was used in western blot to evaluate the therapeutic effect of an HSP-90 inhibitor on MET-amplified cancer cells
Sat Jan 01 00:00:00 EST 2011
HER2 status in a population-derived breast cancer cohort: discordances during tumor progression.
Breast cancer research and treatment
Wilking U,Karlsson E,Skoog L,Hatschek T,Lidbrink E,Elmberger G,Johansson H,Lindström L,Bergh J
MA5-14057 was used in immunohistochemistry to investigate the HER2 status in a breast cancer population
Sat Jan 01 00:00:00 EST 2011
Recurrence of benign meningiomas: predictive value of proliferative index, BCL2, p53, hormonal receptors and HER2 expression.
British journal of neurosurgery
Abdelzaher E,El-Gendi SM,Yehya A,Gowil AG
MA5-14057 was used in immunohistochemistry to identify biomarkers that predict the recurrence of benign meningiomas
Thu Dec 01 00:00:00 EST 2011
A DNA vaccine against ERBB2 impairs chemical carcinogenesis in random-bred hamsters.
Cancer prevention research (Philadelphia, Pa.)
Berta GN,Sprio AE,Iezzi M,Spadaro M,Cappia S,Salamone P,Di Scipio F,Mognetti B,Papotti M,Musiani P,Forni G,Cavallo F
MA5-14057 was used in immunohistochemistry to investigate the effect of repeated DNA vaccinations against ERBB2 on chemical carcinogenesis in hamsters
Fri Jul 01 00:00:00 EDT 2011
HER-2 signaling, acquisition of growth factor independence, and regulation of biological networks associated with cell transformation.
Cancer research
Bollig-Fischer A,Dziubinski M,Boyer A,Haddad R,Giroux CN,Ethier SP
MA5-14057 was used in immunoprecipitation and western blot to study the role of HER-2 signaling in the regulation of biological networks associated with cell transformation
Fri Oct 15 00:00:00 EDT 2010
Detection of minimal residual disease in blood and bone marrow in early stage breast cancer.
Cancer
Krishnamurthy S,Cristofanilli M,Singh B,Reuben J,Gao H,Cohen EN,Andreopoulou E,Hall CS,Lodhi A,Jackson S,Lucci A
MA5-14057 was used in immunohistochemistry to study the presence of circulating tumor cells in blood and disseminated tumor cells in bone marrow of women with early stage breast cancer
Thu Jul 15 00:00:00 EDT 2010
Mechanistic and signaling analysis of Muc4-ErbB2 signaling module: new insights into the mechanism of ligand-independent ErbB2 activity.
Journal of cellular physiology
Kozloski GA,Carraway CA,Carraway KL
MA5-14057 was used in western blot to investigate the mechanism for the reponse of ErbB2 signaling to Muc4
Wed Sep 01 00:00:00 EDT 2010
Comparison of central HER2 testing with quantitative total HER2 expression and HER2 homodimer measurements using a novel proximity-based assay.
American journal of clinical pathology
Huang W,Reinholz M,Weidler J,Yolanda L,Paquet A,Whitcomb J,Lingle W,Jenkins RB,Chen B,Larson JS,Tan Y,Sherwood T,Bates M,Perez EA
MA5-14057 was used in ELISA to develop and evaluate a novel proximity-based assay for quantitating total HER2 expression and HER2 homodimer
Sun Aug 01 00:00:00 EDT 2010
Low Level of Her-2 Locus Amplification by Fluorescent In Situ Hybridization Does Not Correlate with Her-2 Protein Overexpression by Immunohistochemistry in Barrett's Esophagus.
Journal of oncology
Rygiel AM,Milano F,Ten Kate FJ,Bergman JJ,Krishnadath KK
MA5-14057 was used in immunohistochemistry to study the correlation of Her-2 locus amplification with Her-2 protein overexpression in patients with Barrett's esophagus and esophageal adenocarcinoma
Thu Jul 14 00:00:00 EDT 2011
Vaccination with a plasmid DNA encoding HER-2/neu together with low doses of GM-CSF and IL-2 in patients with metastatic breast carcinoma: a pilot clinical trial.
Journal of translational medicine
Norell H,Poschke I,Charo J,Wei WZ,Erskine C,Piechocki MP,Knutson KL,Bergh J,Lidbrink E,Kiessling R
MA5-14057 was used in immunohistochemistry to study the therapeutic potential of HER-2/neu vaccination plus low doses of GM-CSF and IL-2 in metastatic breast carcinoma
Mon Jun 07 00:00:00 EDT 2010
Trastuzumab mediated T-cell response against HER-2/neu overexpressing esophageal adenocarcinoma depends on intact antigen processing machinery.
PloS one
Milano F,Guarriera M,Rygiel AM,Krishnadath KK
MA5-14057 was used in immunocytochemistry to investigate the mechanism of trastuzumab-induced immune response against esophageal adenocarcinoma
Thu Aug 26 00:00:00 EDT 2010
Triple receptor-negative breast cancer: the effect of race on response to primary systemic treatment and survival outcomes.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology
Dawood S,Broglio K,Kau SW,Green MC,Giordano SH,Meric-Bernstam F,Buchholz TA,Albarracin C,Yang WT,Hennessy BT,Hortobagyi GN,Gonzalez-Angulo AM
MA5-14057 was used in immunohistochemistry to investigate the effect of race on the therapeutic outcome from the treatment of triple receptor-negative breast cancer
Sat Jan 10 00:00:00 EST 2009
Merlin regulates transmembrane receptor accumulation and signaling at the plasma membrane in primary mouse Schwann cells and in human schwannomas.
Oncogene
Lallemand D,Manent J,Couvelard A,Watilliaux A,Siena M,Chareyre F,Lampin A,Niwa-Kawakita M,Kalamarides M,Giovannini M
MA5-14057 was used in immunohistochemistry to study the role of merlin on receptor accumulation and signaling at the plasma membrane in normal and tumorigenic Schwann cells
Thu Feb 12 00:00:00 EST 2009
Immunohistochemical characterization of subtypes of male breast carcinoma.
Breast cancer research : BCR
Ge Y,Sneige N,Eltorky MA,Wang Z,Lin E,Gong Y,Guo M
MA5-14057 was used in immunohistochemistry to study the immunohistochemistry of subtypes of male breast carcinoma.
Mon Jan 18 00:00:00 EST 2010
Even low-level HER2 expression may be associated with worse outcome in node-positive breast cancer.
The American journal of surgical pathology
Gilcrease MZ,Woodward WA,Nicolas MM,Corley LJ,Fuller GN,Esteva FJ,Tucker SL,Buchholz TA
MA5-14057 was used in immunohistochemistry to study the association of even low-level HER2 expression with poor outcome in node-positive breast cancer
Fri May 01 00:00:00 EDT 2009
Implementation of American Society of Clinical Oncology/College of American Pathologists HER2 Guideline Recommendations in a tertiary care facility increases HER2 immunohistochemistry and fluorescence in situ hybridization concordance and decreases the number of inconclusive cases.
Archives of pathology & laboratory medicine
Middleton LP,Price KM,Puig P,Heydon LJ,Tarco E,Sneige N,Barr K,Deavers MT
MA5-14057 was used in immunohistochemistry to study the clinical outcomes of HER2 testing after implementation of ASCO/CAP guideline recommendations
Fri May 01 00:00:00 EDT 2009
Performance of chromogenic in situ hybridization on testing HER2 Status in breast carcinomas with chromosome 17 polysomy and equivocal (2+) herceptest results: a study of two institutions using the conventional and new ASCO/CAP scoring criteria.
American journal of clinical pathology
Gong Y,Sweet W,Duh YJ,Greenfield L,Tarco E,Trivedi S,Symmans WF,Isola J,Sneige N
MA5-14057 was used in immunohistochemistry to evaluate CISH and FISH for measuring HER2 status in breast carcinoma using the conventional and new ASCO/CAP scoring criteria
Sat Aug 01 00:00:00 EDT 2009
Tiam1-deficiency impairs mammary tumor formation in MMTV-c-neu but not in MMTV-c-myc mice.
Journal of cancer research and clinical oncology
Strumane K,Rygiel T,van der Valk M,Collard JG
MA5-14057 was used in western blot to study the role of tiam1 in mammary tumor formation in MMTV-c-neu and MMTV-c-myc mice
Thu Jan 01 00:00:00 EST 2009
HER-2/neu (c-erbB-2) oncoprotein in hyperplastic endometrial polyps detected in two cats.
Journal of feline medicine and surgery
Misirlioglu D,Nak D,Ozyigit MO,Nak Y,Akkoc A
MA5-14057 was used in immunohistochemistry to study the HER-2/neu (c-erbB-2) oncoprotein in hyperplastic endometrial polyps detected in two cats
Thu Oct 01 00:00:00 EDT 2009
A novel proximity assay for the detection of proteins and protein complexes: quantitation of HER1 and HER2 total protein expression and homodimerization in formalin-fixed, paraffin-embedded cell lines and breast cancer tissue.
Diagnostic molecular pathology : the American journal of surgical pathology, part B
Shi Y,Huang W,Tan Y,Jin X,Dua R,Penuel E,Mukherjee A,Sperinde J,Pannu H,Chenna A,DeFazio-Eli L,Pidaparthi S,Badal Y,Wallweber G,Chen L,Williams S,Tahir H,Larson J,Goodman L,Whitcomb J,Petropoulos C,Winslow J
MA5-14057 was used in immunocytochemistry to develop a novel proximity assay for detecting HER proteins and homodimers in formalin-fixed cell lines and breast tumor tissues
Sun Mar 01 00:00:00 EST 2009
Differential binding patterns of monoclonal antibody 2C4 to the ErbB3-p185her2/neu and the EGFR-p185her2/neu complexes.
Oncogene
Cai Z,Zhang G,Zhou Z,Bembas K,Drebin JA,Greene MI,Zhang H
MA5-14057 was used in western blot to investigate the binding patterns of monoclonal antibody 2C4 to the ErbB3-Her2 and the EGFR-Her2 complexes
Thu Jun 19 00:00:00 EDT 2008
Distinctive expression pattern of ErbB family receptors signifies an aggressive variant of bladder cancer.
The Journal of urology
Kassouf W,Black PC,Tuziak T,Bondaruk J,Lee S,Brown GA,Adam L,Wei C,Baggerly K,Bar-Eli M,McConkey D,Czerniak B,Dinney CP
MA5-14057 was used in immunohistochemistry to investigate the association of expression of various members of ErbB family receptors with progression of urothelial carcinoma
Tue Jan 01 00:00:00 EST 2008
Geldanamycin-induced down-regulation of ErbB2 from the plasma membrane is clathrin dependent but proteasomal activity independent.
Molecular cancer research : MCR
Pedersen NM,Madshus IH,Haslekås C,Stang E
MA5-14057 was used in western blot to study the mechanism of Geldanamycin-induced down-regulation of ErbB2 from the plasma membrane
Sat Mar 01 00:00:00 EST 2008
HER2 expression and efficacy of preoperative paclitaxel/FAC chemotherapy in breast cancer.
Breast cancer research and treatment
Andre F,Mazouni C,Liedtke C,Kau SW,Frye D,Green M,Gonzalez-Angulo AM,Symmans WF,Hortobagyi GN,Pusztai L
MA5-14057 was used in immunohistochemistry to study the correlation between HER2 expression and pathologic complete response to paclitaxel/FAC preoperative chemotherapy in breast cancer
Sat Mar 01 00:00:00 EST 2008
Epitope mapping and structural analysis of an anti-ErbB2 antibody A21: Molecular basis for tumor inhibitory mechanism.
Proteins
Hu S,Zhu Z,Li L,Chang L,Li W,Cheng L,Teng M,Liu J
MA5-14057 was used in western blot to study the tumor inhibitory mechanism of an anti-ErbB2 antibody
Fri Feb 15 00:00:00 EST 2008
Apocrine carcinomas of the breast in Turkish women: hormone receptors, c-erbB-2 and p53 immunoexpression.
Pathology, research and practice
Kaya H,Bozkurt SU,Erbarut I,Djamgoz MB
MA5-14057 was used in immunohistochemistry to perform immunohistochemical studies of apocrine carcinomas in Turkish women with breast cancer
Thu Aug 21 00:00:00 EDT 2008
Lipid raft localization of ErbB2 in vestibular schwannoma and schwann cells.
Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
Brown KD,Hansen MR
MA5-14057 was used in western blot to examine the ErbB2 localization in vestibular schwannoma and schwann cells
Tue Jan 01 00:00:00 EST 2008
Predictive value of serum anti-p53 antibodies, carcino-embryonic antigen, carbohydrate antigen 15-3, estrogen receptor, progesterone receptor and human epidermal growth factor receptor-2 in taxane-based and anthracycline-based neoadjuvant chemotherapy in locally advanced breast cancer patients.
Anti-cancer drugs
Bao H,Yu D,Wang J,Qiu T,Yang J,Wang L
MA5-14057 was used in immunohistochemistry to investigate the prognostic markers of taxane-based and anthracycline-based neoadjuvant chemotherapy for breast carcinoma
Sat Mar 01 00:00:00 EST 2008
Loss of annexin A1 expression in breast cancer progression.
Applied immunohistochemistry & molecular morphology : AIMM
Cao Y,Li Y,Edelweiss M,Arun B,Rosen D,Resetkova E,Wu Y,Liu J,Sahin A,Albarracin CT
MA5-14057 was used in immunohistochemistry to study ANXA1 expression during the progression of breast carcinomas
Mon Dec 01 00:00:00 EST 2008
Determination of oestrogen-receptor status and ERBB2 status of breast carcinoma: a gene-expression profiling study.
The Lancet. Oncology
Gong Y,Yan K,Lin F,Anderson K,Sotiriou C,Andre F,Holmes FA,Valero V,Booser D,Pippen JE,Vukelja S,Gomez H,Mejia J,Barajas LJ,Hess KR,Sneige N,Hortobagyi GN,Pusztai L,Symmans WF
MA5-14057 was used in immunohistochemistry to develop a method for profiling oestrogen-receptor status and ERBB2 status in breast carcinoma
Thu Mar 01 00:00:00 EST 2007
Breast cancer survival and tumor characteristics in premenopausal women carrying the CHEK2*1100delC germline mutation.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology
Schmidt MK,Tollenaar RA,de Kemp SR,Broeks A,Cornelisse CJ,Smit VT,Peterse JL,van Leeuwen FE,Van't Veer LJ
MA5-14057 was used in immunohistochemistry to study breast cancer survival and tumor characteristics in premenopausal women carrying the CHEK2*1100delC germline mutation
Mon Jan 01 00:00:00 EST 2007
Breast tumor kinase (protein tyrosine kinase 6) regulates heregulin-induced activation of ERK5 and p38 MAP kinases in breast cancer cells.
Cancer research
Ostrander JH,Daniel AR,Lofgren K,Kleer CG,Lange CA
MA5-14057 was used in western blot to study the mechanism by which breast tumor kinase regulates the activation of ERK5 and p38 MAP kinases in breast cancer cells
Tue May 01 00:00:00 EDT 2007
Erlotinib directly inhibits HER2 kinase activation and downstream signaling events in intact cells lacking epidermal growth factor receptor expression.
Cancer research
Schaefer G,Shao L,Totpal K,Akita RW
MA5-14057 was used in western blot to study the ability of erlotinib to directly inhibit HER2 kinase in intact cells lacking EGFR
Thu Feb 01 00:00:00 EST 2007
Gene expression profiling and histopathological characterization of triple-negative/basal-like breast carcinomas.
Breast cancer research : BCR
Kreike B,van Kouwenhove M,Horlings H,Weigelt B,Peterse H,Bartelink H,van de Vijver MJ
MA5-14057 was used in immunohistochemistry to study triple negative breast carcinoma histopathology and gene expression patterns in order to define clinically significant sub-groups
Tue Mar 11 00:00:00 EDT 2008
Kinetics of serum HER-2/neu changes in patients with HER-2-positive primary breast cancer after initiation of primary chemotherapy.
Cancer
Mazouni C,Hall A,Broglio K,Fritsche H,Andre F,Esteva FJ,Hortobagyi GN,Buzdar AU,Pusztai L,Cristofanilli M
MA5-14057 was used in immunohistochemistry to study the value of serum HER-2 receptor extracellular domain measurements for predicting the response to chemotherapy in primary breast cancer patients
Thu Feb 01 00:00:00 EST 2007
Species differences in renal Src activity direct EGF receptor regulation in life or death response to EGF.
American journal of physiology. Renal physiology
Kiley SC,Chevalier RL
MA5-14057 was used in western blot to examine the mechanism for opposite EGF responses among different species
Sat Sep 01 00:00:00 EDT 2007
Primary neuroendocrine carcinoma of the breast: a case report.
Tumori
Yaren A,Kelten C,Akbulut M,Teke Z,Duzcan E,Erdem E
MA5-14057 was used in immunohistochemistry to report on a case of primary neuroendocrine carcinoma of the breast
Tue Dec 11 00:00:00 EST 2007
Abundance and localization of skeletal muscle-related erbB2 may stimulate tumour growth during initial stages of oral oncogenesis.
Journal of musculoskeletal & neuronal interactions
Vairaktaris E,Moulavassili P,Loukeri S,Spyridonidou S,Yapijakis C,Vassiliou S,Nkenke E,Vylliotis A,Papakosta V,Lazaris A,Patsouris E
MA5-14057 was used in immunohistochemistry to study the role of skeletal muscle-related erbB2 in stimulating tumor growth in oral oncogenesis
Wed Oct 17 00:00:00 EDT 2007
The ErbB4 receptor in fetal rat lung fibroblasts and epithelial type II cells.
Biochimica et biophysica acta
Liu W,Zscheppang K,Murray S,Nielsen HC,Dammann CE
MA5-14057 was used in western blot to investigate the role of ErbB4 receptor in fetal rat lung fibroblasts and epithelial type II cells
Sun Jul 01 00:00:00 EDT 2007
Clonal nature of sclerosing polycystic adenosis of salivary glands demonstrated by using the polymorphism of the human androgen receptor (HUMARA) locus as a marker.
The American journal of surgical pathology
Skálová A,Gnepp DR,Simpson RH,Lewis JE,Janssen D,Sima R,Vanecek T,Di Palma S,Michal M
MA5-14057 was used in immunohistochemistry to investigate clonality of sclerosing polycystic adenosis by human androgen receptor polymorphism
Tue Aug 01 00:00:00 EDT 2006
Geldanamycin stimulates internalization of ErbB2 in a proteasome-dependent way.
Journal of cell science
Lerdrup M,Hommelgaard AM,Grandal M,van Deurs B
MA5-14057 was used in western blot to investigate ErbB2 internalization
Sun Jan 01 00:00:00 EST 2006
MUC4 expression and its relation to ErbB2 expression, apoptosis, proliferation, differentiation, and tumor stage in non-small cell lung cancer (NSCLC).
Pathology, research and practice
Karg A,Dinç ZA,Başok O,Uçvet A
MA5-14057 was used in immunohistochemistry to study the expression of MUC4 in different stages of non-small cell lung cancer and its relationship with ErbB2 expression
Thu Sep 21 00:00:00 EDT 2006
[An analysis of genetic transmission in a father and son with osteosarcoma].
Acta orthopaedica et traumatologica turcica
Tokatli F,Alas RC,Altaner S,Pala F,Uygun K,Uzal C,Yalniz E
MA5-14057 was used in immunohistochemistry to report on a case of a father and son with familial osteosarcoma
Fri Jul 20 00:00:00 EDT 2007
CD44 expression is associated with increased survival in node-negative invasive breast carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research
Diaz LK,Zhou X,Wright ET,Cristofanilli M,Smith T,Yang Y,Sneige N,Sahin A,Gilcrease MZ
MA5-14057 was used in immunohistochemistry to study the prognostic significance of CD44 expression in node-negative invasive breast carcinoma
Sun May 01 00:00:00 EDT 2005
Beta4 integrin subunit gene expression correlates with tumor size and nuclear grade in early breast cancer.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
Diaz LK,Cristofanilli M,Zhou X,Welch KL,Smith TL,Yang Y,Sneige N,Sahin AA,Gilcrease MZ
MA5-14057 was used in immunohistochemistry to study the relationship between beta4 integrin subunit expression and early breast tumor size and nuclear grade
Thu Sep 01 00:00:00 EDT 2005
Non-invasive (intracapsular) carcinoma ex pleomorphic adenoma: recognition of focal carcinoma by HER-2/neu and MIB1 immunohistochemistry.
Histopathology
Di Palma S,Skálová A,Vanìèek T,Simpson RH,Stárek I,Leivo I
MA5-14057 was used in immunohistochemistry to characterize non-invasive carcinoma ex pleomorphic adenoma through HER-2/neu and MIB1 expression
Tue Feb 01 00:00:00 EST 2005
Cystic hypersecretory carcinoma: rare and poorly recognized variant of intraductal carcinoma of the breast. Report of five cases.
Histopathology
Skalova A,Ryska A,Kajo K,Di Palma S,Kinkor Z,Michal M
MA5-14057 was used in immunohistochemistry to report the clinical cases of cystic hypersecretory carcinoma
Sat Jan 01 00:00:00 EST 2005
Vitamin D receptor agonists induce prostatic acid phosphatase to reduce cell growth and HER-2 signaling in LNCaP-derived human prostate cancer cells.
The Journal of steroid biochemistry and molecular biology
Stewart LV,Lyles B,Lin MF,Weigel NL
MA5-14057 was used in western blot to study the effects of vitamin D receptor agonists on androgen-dependent LNCaP human prostate cancer cell growth
Sat Oct 01 00:00:00 EDT 2005
The presence of serum anti-p53 antibodies from patients with invasive ductal carcinoma of breast: correlation to other clinical and biological parameters.
Breast cancer research and treatment
Gao RJ,Bao HZ,Yang Q,Cong Q,Song JN,Wang L
MA5-14057 was used in immunohistochemistry to investigate the presence and utility of p53 antibodies in patients with breast cancer
Thu Sep 01 00:00:00 EDT 2005
Chemokine receptor CXCR4 expression in breast cancer as a potential predictive marker of isolated tumor cells in bone marrow.
Clinical & experimental metastasis
Cabioglu N,Sahin A,Doucet M,Yavuz E,Igci A,O Yildirim E,Aktas E,Bilgic S,Kiran B,Deniz G,Price JE
MA5-14057 was used in immunohistochemistry to study CXCR4 receptor expression in breast cancer as a predictive marker for isolated tumor cells in bone marrow
Tue Oct 18 00:00:00 EDT 2005
Concordant loss of fragile gene expression early in breast cancer development.
Pathology international
Guler G,Uner A,Guler N,Han SY,Iliopoulos D,McCue P,Huebner K
MA5-14057 was used in immunohistochemistry to investigate the expression of the fragile gene in breast cancer development
Mon Aug 01 00:00:00 EDT 2005
Ductal carcinoma in situ with spindle cells: a potential diagnostic pitfall in the evaluation of breast lesions.
Histopathology
Tan PH,Lui GG,Chiang G,Yap WM,Poh WT,Bay BH
MA5-14057 was used in immunohistochemistry to characterize 11 cases of ductal carcinoma in situ with spindle cells
Fri Oct 01 00:00:00 EDT 2004
In vitro chemoresistance and biomarker profiles are unique for histologic subtypes of epithelial ovarian cancer.
Gynecologic oncology
Cloven NG,Kyshtoobayeva A,Burger RA,Yu IR,Fruehauf JP
MA5-14057 was used in immunohistochemistry to study whether there is a relationship between histologic subtype of epithelial ovarian cancer and chemoresistance
Thu Jan 01 00:00:00 EST 2004
Role of ErbB2 in Corneal Epithelial Wound Healing.
Investigative ophthalmology & visual science
Xu KP,Riggs A,Ding Y,Yu FS
MA5-14057 was used in western blot to investigate the function of ErbB2 in the regulation of cell migration during corneal epithelial wound healing
Wed Dec 01 00:00:00 EST 2004
Vitamin D receptor status alters mammary gland morphology and tumorigenesis in MMTV-neu mice.
Carcinogenesis
Zinser GM,Welsh J
MA5-14057 was used in immunohistochemistry to study the effect of vitamin D receptor gene dosage on mammary gland morphology and tumorigenesis
Wed Dec 01 00:00:00 EST 2004
Inability of immunohistochemistry to predict clinical outcomes of endometrial cancer patients.
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society
Gossett DR,Alo P,Bristow RE,Galati M,Kyshtoobayeva A,Fruehauf J,Montz FJ
MA5-14057 was used in immunohistochemistry to study the inability of immunohistochemistry to predict clinical outcome in endometrial cancer
Thu May 27 00:00:00 EDT 2004
Autocrine extracellular signal-regulated kinase (ERK) activation in normal human keratinocytes: metalloproteinase-mediated release of amphiregulin triggers signaling from ErbB1 to ERK.
Molecular biology of the cell
Kansra S,Stoll SW,Johnson JL,Elder JT
MA5-14057 was used in western blot to investigate the mechanism of ERK autocrine activation in normal human keratinocytes
Wed Sep 01 00:00:00 EDT 2004
Automated quantification of apoptosis after neoadjuvant chemotherapy for breast cancer: early assessment predicts clinical response.
Clinical cancer research : an official journal of the American Association for Cancer Research
Davis DW,Buchholz TA,Hess KR,Sahin AA,Valero V,McConkey DJ
MA5-14057 was used in immunohistochemistry to study whether early assessment of apoptosis following breast cancer neoadjuvant chemotherapy predicts clinical response
Sat Mar 01 00:00:00 EST 2003
Jun activation domain binding protein 1 expression is associated with low p27(Kip1)levels in node-negative breast cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research
Esteva FJ,Sahin AA,Rassidakis GZ,Yuan LX,Smith TL,Yang Y,Gilcrease MZ,Cristofanilli M,Nahta R,Pusztai L,Claret FX
MA5-14057 was used in immunohistochemistry to study the prognostic significance of JAB1 and p27(Kip1) in node-negative breast cancer.
Sat Nov 15 00:00:00 EST 2003
Establishment and characterization of cancer cell cultures and xenografts derived from primary or metastatic Mullerian cancers.
Clinical cancer research : an official journal of the American Association for Cancer Research
Verschraegen CF,Hu W,Du Y,Mendoza J,Early J,Deavers M,Freedman RS,Bast RC,Kudelka AP,Kavanagh JJ,Giovanella BC
MA5-14057 was used in immunocytochemistry to characterize cell cultures and xenografts derived from patients with ovarian cancer
Sat Feb 01 00:00:00 EST 2003
Alpha6beta1 integrin induces proteasome-mediated cleavage of erbB2 in breast cancer cells.
Oncogene
Shimizu H,Seiki T,Asada M,Yoshimatsu K,Koyama N
MA5-14057 was used in western blot to study the role of alpha6beta1 integrin in inducing proteasome-mediated cleavage of erbB2 in breast cancer cells
Thu Feb 13 00:00:00 EST 2003
Spontaneous activation and signaling by overexpressed epidermal growth factor receptors in glioblastoma cells.
International journal of cancer
Thomas CY,Chouinard M,Cox M,Parsons S,Stallings-Mann M,Garcia R,Jove R,Wharen R
MA5-14057 was used in western blot to study the role of endogenously overexpressed EGF receptors in glioblastoma cells
Mon Mar 10 00:00:00 EST 2003
Breast carcinoma in pregnant women: assessment of clinicopathologic and immunohistochemical features.
Cancer
Middleton LP,Amin M,Gwyn K,Theriault R,Sahin A
MA5-14057 was used in immunohistochemistry to study the histopathology and immunohistochemistry of breast carcinoma in pregnant women
Mon Sep 01 00:00:00 EDT 2003
Mucin-rich variant of salivary duct carcinoma: a clinicopathologic and immunohistochemical study of four cases.
The American journal of surgical pathology
Simpson RH,Prasad AR,Lewis JE,Skálová A,David L
MA5-14057 was used in immunohistochemistry to study the clinicopathology and immunohistochemistry of four cases of mucin-rich variant of salivary duct carcinoma
Fri Aug 01 00:00:00 EDT 2003
A chimeric multi-human epidermal growth factor receptor-2 B cell epitope peptide vaccine mediates superior antitumor responses.
Journal of immunology (Baltimore, Md. : 1950)
Dakappagari NK,Pyles J,Parihar R,Carson WE,Young DC,Kaumaya PT
MA5-14057 was used in western blot to develop and evaluate a multi-epitope vaccine targeting HER-2
Tue Apr 15 00:00:00 EDT 2003
Her2/neu overexpression in differentiated thyroid carcinomas predicts metastatic disease.
Virchows Archiv : an international journal of pathology
Kremser R,Obrist P,Spizzo G,Erler H,Kendler D,Kemmler G,Mikuz G,Ensinger C
MA5-14057 was used in immunohistochemistry to study the prognostic value of Her2/neu overexpression in differentiated thyroid carcinomas
Tue Apr 01 00:00:00 EST 2003
Heregulin and HER2 signaling selectively activates c-Src phosphorylation at tyrosine 215.
FEBS letters
Vadlamudi RK,Sahin AA,Adam L,Wang RA,Kumar R
MA5-14057 was used in western blot to study the ability of heregulin and HER2 signaling to upregulate c-Src tyrosine 215 phosphoylation and subsequently upregulate FAK tyrosine 861 phosphorylation in breast cancer cells
Thu May 22 00:00:00 EDT 2003
Muc4/sialomucin complex, the intramembrane ErbB2 ligand, translocates ErbB2 to the apical surface in polarized epithelial cells.
The Journal of biological chemistry
Ramsauer VP,Carraway CA,Salas PJ,Carraway KL
MA5-14057 was used in western blot to investigate the translocation of ErbB2 to the apical surface in polarized epithelial cells
Fri Aug 08 00:00:00 EDT 2003
Phase II study of weekly docetaxel and trastuzumab for patients with HER-2-overexpressing metastatic breast cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology
Esteva FJ,Valero V,Booser D,Guerra LT,Murray JL,Pusztai L,Cristofanilli M,Arun B,Esmaeli B,Fritsche HA,Sneige N,Smith TL,Hortobagyi GN
MA5-14057 was used in immunohistochemistry to study the clinical effect of a docetaxel and trastuzumab combination treatment in HER-2-overexpressing metastatic breast cancer
Mon Apr 01 00:00:00 EST 2002
Cyclooxygenase-2 expression in human breast cancers and adjacent ductal carcinoma in situ.
Cancer research
Half E,Tang XM,Gwyn K,Sahin A,Wathen K,Sinicrope FA
MA5-14057 was used in immunohistochemistry to study the expression of COX-2 in human breast cancers and adjacent ductal carcinoma in situ
Fri Mar 15 00:00:00 EST 2002
Clinical significance of serum and urinary c-erbB-2 levels in colorectal cancer.
Cancer letters
Tsigris C,Karayiannakis AJ,Zbar A,Syrigos KN,Baibas N,Diamantis T,Alexiou D
MA5-14057 was used in immunohistochemistry to investigate the prognostic usefulness of c-erbB-2 for colorectal cancer
Mon Oct 28 00:00:00 EST 2002
Classification of low-grade neuroendocrine tumors of midgut and unknown origin.
Human pathology
Van Eeden S,Quaedvlieg PF,Taal BG,Offerhaus GJ,Lamers CB,Van Velthuysen ML
MA5-14057 was used in immunohistochemistry to study whether refining the grading of low-grade neuroendocrine tumors of the midgut and unknown origin is of prognostic/predictive value
Fri Nov 01 00:00:00 EST 2002
Tyrphostin AG825 triggers p38 mitogen-activated protein kinase-dependent apoptosis in androgen-independent prostate cancer cells C4 and C4-2.
Cancer research
Murillo H,Schmidt LJ,Tindall DJ
MA5-14057 was used in western blot to study the role of p38 MAP kinase in the induction of apoptosis in androgen-independent prostate cancer cells by the EGFR inhibitor typhostin AG825
Mon Oct 15 00:00:00 EDT 2001
The tyrosine kinase inhibitor ZD1839 ("Iressa") inhibits HER2-driven signaling and suppresses the growth of HER2-overexpressing tumor cells.
Cancer research
Moasser MM,Basso A,Averbuch SD,Rosen N
MA5-14057 was used in western blot to study the inhibition of HER2-driven signaling and growth suppression of HER2-overexpressing tumor cells by Iressa
Mon Oct 01 00:00:00 EDT 2001