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F-Actin Polyclonal Antibody

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F-Actin Polyclonal Antibody

Product Details

BS-1571R

Applications
Tested Dilution
Publications

Western Blot (WB)

1:200
-

Immunohistochemistry (Paraffin) (IHC (P))

1:200
-

Immunocytochemistry (ICC/IF)

1:50-1:200
-

Flow Cytometry (Flow)

1:20-1:100
-

ELISA (ELISA)

1:500-1:1,000
-
Product Specifications

Species Reactivity

Dog, Chicken, Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

KLH conjugated synthetic peptide derived from human F-actin capping protein alpha subunit, amino acids 1-50.
3D Epitope / Immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Amount

100 µg

Purification

Protein A

Storage buffer

0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol

Contains

0.02% ProClin 300

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

Target Information

This gene encodes one of six different actin proteins. Actins are highly conserved proteins that are involved in cell motility, structure, and integrity. This actin is a major constituent of the contractile apparatus and one of the two nonmuscle cytoskeletal actins.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Actin is a protein with a high degree of evolutionary conservation that undergoes polymerization to generate filaments, which subsequently assemble into interconnected networks within the cytoplasm of cells.; Actin, cytoplasmic 1; Atcb; Bact; actin; beta cytoskeletal actin; Beta-actin; cytoplasmic 1; cytoplasmic beta-actin; I(2)-actin; PS1TP5-binding protein 1; unnamed protein product

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Gene Aliases: ACTB; actin; Actx; Bact; beta-actin; BKRNS; BNS; BRWS1; CSMH; DDS1; E430023M04Rik; PS1TP5BP1; THC8

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UniProt ID: (Human) P60709, (Chicken) P60706, (Dog) O18840, (Rat) P60711, (Mouse) P60710

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Entrez Gene ID: (Human) 60, (Chicken) 396526, (Dog) 403580, (Rat) 81822, (Mouse) 11461

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Function(s)
nucleotide binding structural constituent of cytoskeleton protein binding ATP binding hydrolase activity ATPase activity kinesin binding protein kinase binding nitric-oxide synthase regulator activity Tat protein binding nucleosomal DNA binding identical protein binding tau protein binding nitric-oxide synthase binding structural constituent of postsynaptic actin cytoskeleton transporter regulator activity RNA polymerase II core promoter proximal region sequence-specific DNA binding RNA polymerase II distal enhancer sequence-specific DNA binding actin and actin related protein actin or actin-binding cytoskeletal protein cytoskeletal protein
Process(es)
morphogenesis of a polarized epithelium chromatin remodeling regulation of transcription from RNA polymerase II promoter cytoskeleton organization establishment or maintenance of cell polarity axonogenesis positive regulation of cell proliferation substantia nigra development regulation of mitotic metaphase/anaphase transition adherens junction assembly maintenance of blood-brain barrier regulation of apoptotic process apical protein localization positive regulation of T cell differentiation negative regulation of cell differentiation positive regulation of cell differentiation positive regulation of myoblast differentiation positive regulation of transcription, DNA-templated cell motility regulation of norepinephrine uptake positive regulation of norepinephrine uptake regulation of cell cycle regulation of G0 to G1 transition platelet aggregation protein localization to adherens junction cellular response to cytochalasin B postsynaptic actin cytoskeleton organization regulation of transepithelial transport regulation of synaptic vesicle endocytosis positive regulation of stem cell population maintenance regulation of protein localization to plasma membrane positive regulation of double-strand break repair via homologous recombination regulation of G1/S transition of mitotic cell cycle regulation of double-strand break repair positive regulation of double-strand break repair regulation of nucleotide-excision repair retina homeostasis ATP-dependent chromatin remodeling retina development in camera-type eye cellular response to electrical stimulus
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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