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Proteintech
F2RL3 Polyclonal Antibody
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Product Details
25306-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
F2RL3 Fusion Protein Ag20801 (305-385 aa encoded by BC074782)
Conjugate
Form
Liquid
Concentration
0.29 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: LHYSDPSPS AWGNLYGAYV PSLALSTLNS CVDPFIYYYV SAEFRDKVRA GLFQRSPGDT VASKASAEGG SRGMGTHSSL LQ (305-385 aa encoded by BC074782)
Target Information
Coagulation factor II (thrombin) receptor-like 3 (F2RL3) is a member of the large family of 7-transmembrane-region receptors that couple to guanosine-nucleotide-binding proteins. F2RL3 is also a member of the protease-activated receptor family. F2RL3 is activated by proteolytic cleavage of its extracellular amino terminus. The new amino terminus functions as a tethered ligand and activates the receptor. F2RL3 is activated by thrombin and trypsin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: coagulation factor II (thrombin) receptor-like 3; Coagulation factor II receptor-like 3; F2R like thrombin/trypsin receptor 3; G protein-coupled receptor; G-protein coupled receptor; PAR-4; PAR4; protease-activated receptor-4; Proteinase-activated receptor 4; Thrombin receptor-like 3
Gene Aliases: F2RL3; PAR4
UniProt ID: (Human) Q96RI0, (Mouse) O88634
Entrez Gene ID: (Human) 9002, (Mouse) 14065
signal transduction
G-protein coupled receptor signaling pathway
phospholipase C-activating G-protein coupled receptor signaling pathway
blood coagulation
hemostasis
response to wounding
platelet activation
positive regulation of release of sequestered calcium ion into cytosol
platelet dense granule organization
thrombin receptor signaling pathway
platelet aggregation
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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