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Invitrogen
FADS2 Polyclonal Antibody
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FIGURE: 1 / 9
FADS2 Antibody (PA5-48353) in ICC/IF
Immunocytochemistry analysis of FADS2 in A549 cells. Samples were incubated with FADS2 polyclonal antibody (Product # PA5-48353) using a dilution of 1:25 for 1 h at 37°C followed by Alexa Fluor® 488 conjugated donkey anti-rabbit antibody (green) at a dilution of 1:400 for 50 min at 37°C. Cells were fixed with 4% PFA (20 min) and permeabilized with Triton X-100 (0.1%, 10 min). Cytoplasmic actin was counterstained with Alexa Fluor® 555 (red) conjugated Phalloidin (7 units/mL, 1 h at 37°C). FADS2 immunoreactivity is localized to Cytoplasm and... View More
Product Details
PA5-48353
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide between 79-108 amino acids from the N-terminal region of human FADS2.
Conjugate
Form
Liquid
Concentration
0.48 mg/mL
Purification
Protein A, Antigen affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Predicted to react with monkey based on sequence homology.
Target Information
The protein encoded by this gene is a member of the fatty acid desaturase (FADS) gene family. Desaturase enzymes regulate unsaturation of fatty acids through the introduction of double bonds between defined carbons of the fatty acyl chain. FADS family members are considered fusion products composed of an N-terminal cytochrome b5-like domain and a C-terminal multiple membrane-spanning desaturase portion, both of which are characterized by conserved histidine motifs. This gene is clustered with family members FADS1 and FADS2 at 11q12-q13. 1; this cluster is thought to have arisen evolutionarily from gene duplication based on its similar exon/intron organization.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Acyl-CoA 6-desaturase; D6D; delta(6) desaturase; Delta(6) fatty acid desaturase; delta-6 desaturase; delta-6 fatty acid desaturase; delta-6-desaturase; Fatty acid desaturase 2; linoleoyl-CoA desaturase (delta-6-desaturase)-like 2
Gene Aliases: D6D; DES6; FADS2; FADSD6; LLCDL2; SLL0262; TU13
UniProt ID: (Human) O95864
Entrez Gene ID: (Human) 9415
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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