Serves as a substrate-specific adapter for the CUL3-based ubiquitin-protein E3 ligase complex. Negatively regulates the Wnt signaling pathway via the targeted ubiquitination and subsequent proteolysis of DVL3.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: down regulated by Ctnnb1, a; Down-regulated by CTNNB1 protein A; down-regulated by Ctnnb1, A; family with sequence similarity 126, member A; Hyccin; Protein FAM126A
Gene Aliases: AB030242; DRCTNNB1A; FAM126A; HCC; HLD5; HYCC1; RGD1562906