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Invitrogen
FAM65B Polyclonal Antibody
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Product Details
PA5-97196
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-210 of human FAM65B (NP_0569482)
Conjugate
Form
Liquid
Concentration
1.09 mg/mL
Amount
109 µg
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: MLVGSQSFSP GGPNGIIRSQ SFAGFSGLQE RRSRCNSFIE NSSALKKPQA KLKKMHNLGH KNNNPPKEPQ PKRVEEVYRA LKNGLDEYLE VHQTELDKLT AQLKDMKRNS RLGVLYDLDK QIKTIERYMR RLEFHISKVD ELYEAYCIQR RLQDGASKMK QAFATSPASK AARESLTEIN RSFKEYTENM CTIEVELENL LGEFSIKMKG; Positive Samples: U-87MG, Mouse thymus, Mouse brain, Rat thymus, Rat brain; Cellular Location: Cell projection, Cytoplasm, Mitochondrion, cytoskeleton, filopodium, stereocilium membrane
Target Information
Required for hearing (PubMed:24958875). Involved in skeletal muscle development (PubMed:24687993).
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: family with sequence similarity 65 member B; KIAA0386; myogenesis-related and NCAM-associated protein homolog; protein FAM65B; Rho family-interacting cell polarization regulator 2; unnamed protein product
Gene Aliases: Ab2-162; C6orf32; DFNA21; DFNB104; DIFF40; DIFF48; FAM65B; KIAA0386; MYONAP; PL48; RGD1306939; RIPOR2
UniProt ID: (Rat) Q7TP54, (Mouse) Q80U16, (Human) Q9Y4F9
Entrez Gene ID: (Rat) 306934, (Mouse) 193385, (Human) 9750
cellular iron ion homeostasis
sensory perception of sound
chemotaxis
cell adhesion
negative regulation of cell adhesion
muscle organ development
negative regulation of signal transduction
cell differentiation
negative regulation of Rho protein signal transduction
negative regulation of T cell proliferation
positive regulation of myoblast differentiation
positive regulation of filopodium assembly
regulation of cell cycle
positive regulation of neutrophil chemotaxis
regulation of mitotic spindle assembly
positive regulation of myoblast fusion
negative regulation of establishment of T cell polarity
negative regulation of protein localization to cell leading edge
cellular response to chemokine
regulation of establishment of cell polarity
positive regulation of neutrophil extravasation
negative regulation of T cell migration
negative regulation of Rho guanyl-nucleotide exchange factor activity
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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