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Invitrogen
FAM83D Polyclonal Antibody
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Product Details
PA5-71098
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
synthetic peptide directed towards the C-terminal region of human FAM83D
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Amount
50 µg
Purification
Affinity chromatography
Storage buffer
PBS with 2% sucrose
Contains
0.09% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
This target displays homology in the following species: Horse: 79%; Human: 100%; Mouse: 86%; Rabbit: 86%; Rat: 79%
Target Information
Probable proto-oncogene that regulates cell proliferation, growth, migration and epithelial to mesenchymal transition. Through the degradation of FBXW7, may act indirectly on the expression and downstream signaling of MTOR, JUN and MYC (PubMed:24344117). May play also a role in cell proliferation through activation of the ERK1/ERK2 signaling cascade (PubMed:25646692). May also be important for proper chromosome congression and alignment during mitosis through its interaction with KIF22.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Protein FAM83D; Spindle protein CHICA; unnamed protein product
Gene Aliases: C20orf129; CHICA; dJ616B8.3; FAM83D
UniProt ID: (Human) Q9H4H8
Entrez Gene ID: (Human) 81610
epithelial to mesenchymal transition
signal transduction
cell proliferation
cell migration
regulation of TOR signaling
regulation of protein catabolic process
cell division
metaphase plate congression
regulation of ERK1 and ERK2 cascade
protein localization to mitotic spindle
positive regulation of cell cycle G1/S phase transition
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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