Immunogen sequence: CYFPFTHPSF EMEINFHGEW LEVLGCGVME QQLVNSAGAQ DRIGWAFGLG LERLAMILYD IPDIRLFWCE DERFLKQFCV SNINQKVKFQ PLSKYPAVIN DISFWLPSEN YAEND
Highest antigen sequence identity to the following orthologs: Mouse - 92%, Rat - 91%.
Alterations and deletions of the FHIT gene are strongly linked to the genesis and establishment of human tumors of the lung, cervix, breast, colon, stomach and pancreas. In normal cells, FHIT may act as a tumor suppressor.
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Protein Aliases: dJ236A3.1 (phenylalanine-tRNA synthetase); dJ520B18.2; dJ520B18.2 (FARS1 (phenylalanine-tRNA synthetase)); FARS1; HSPC320; mitochondrial; mitochondrial PHERS; pheny; phenylalanine translase; phenylalanine tRNA ligase 2; phenylalanine tRNA ligase 2, mitochondrial; phenylalanine--tRNA ligase; Phenylalanine--tRNA ligase, mitochondrial; phenylalanine-tRNA synthetase 1 (mitochondrial); Phenylalanyl-tRNA synthetase; PheRS
Gene Aliases: COXPD14; FARS1; FARS2; HSPC320; PheRS
UniProt ID: (Human) O95363
Entrez Gene ID: (Human) 10667