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Product Details
PA5-145082
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence. Antigen range: 2706-2800. Recombinant protein control fragment (Product #RP-110211).
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_3092110
Product Specific Information
Immunogen sequence: PSFTQSQYSF TIAEDTAIGS TVDTLRILPS QNVWFSTVNG ERPENNKGGV FVIEQETGTI KLDKRLDRET SPAFHFKVAA TIPLDKVDIV FTVDV
Antigen sequence identity: Mouse 88%; Rat 88%
Target Information
FAT1, FAT2, FAT3 and FAT4 are human homologs of Drosophila Fat, which is involved in tumor suppression and planar cell polarity (PCP). The atypical cadherin Fat3 ensures that retinal amacrine cells (ACs) develop this unipolar morphology. Fat3 expression was restricted to the nervous system, for example in the brain, it is expressed in a variety of regions and axon fascicles. However, its strongest expression was observed in the olfactory bulb and retina.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Cadherin family member 15; cadherin-related family member 10; FAT tumor suppressor homolog 3; hFat3; Protocadherin Fat 3
Gene Aliases: CDHF15; CDHR10; FAT3; hFat3; KIAA1989
UniProt ID: (Human) Q8TDW7
Entrez Gene ID: (Human) 120114
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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