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Proteintech

FATP2 Polyclonal Antibody, CoraLite® Plus 488

View all (9) SLC27A2 antibodies

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Product Details

CL488-14048

Applications
Tested Dilution
Publications

Immunocytochemistry (ICC/IF)

1:50-1:500
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

FATP2 fusion protein Ag5217

Conjugate

CoraLite® Plus 488 CoraLite® Plus 488 CoraLite® Plus 488

Excitation/Emission Max

493/522 nm

Form

Liquid

Concentration

1 mg/mL

Amount

100 µg

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol, 0.5% BSA

Contains

0.05% ProClin 300

Storage conditions

-20°C, store in dark

Shipping conditions

Wet ice

Product Specific Information

Immunogen sequence: ESWRSEVTF STPALYIYTS GTTGATLALR TKFSASQFWD DCRKYNVTVI QYIGELLRYL CNSPQKPNDR DHKVRLALGN GLRGDVWRQF VKRFGDICIY EFYAATEGNI GFMNYARKVG AVGRVNYLQK KIITYDLIKY DVEKDEPVRD ENGYCVRVPK GEVGLLVCKI TQLTPFNGYA GAKAQTEKKK LRDVFKKGDL YFNSGDLLMV DHENFIYFHD RVGDTFRWKG ENVATTEVAD TVGLVDFVQE VNVYGVHVPD HEGRIGMASI KMKENHEFDG KKLFQHIADY LPSYARPRFL RIQDTIEITG TFKHRKMTLV EEGFNPAVIK DALYFLDDTA KMYVPMTEDI YNAISAKTLK L

Target Information

The protein encoded by this gene is an isozyme of long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme activates long-chain, branched-chain and very-long-chain fatty acids containing 22 or more carbons to their CoA derivatives. It is expressed primarily in liver and kidney, and is present in both endoplasmic reticulum and peroxisomes but not in mitochondria. Its decreased peroxisomal enzyme activity is in part responsible for the biochemical pathology in X-linked adrenoleukodystrophy.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Arachidonate--CoA ligase; FATP-2; Fatty acid transport protein 2; Fatty-acid-coenzyme A ligase, very long-chain 1; Long-chain fatty acid transport protein 2; Long-chain-fatty-acid--CoA ligase; Phytanate--CoA ligase; Slc27a2; solute carrier family 27 (fatty acid transporter), member 2; solute carrier family 27 (fatty acid transporter), member 32; Solute carrier family 27 member 2; THCA-CoA ligase; unnamed protein product; ve; Very long-chain acyl-CoA synthetase; very long-chain acyl-Coenzyme A dehydrogenase synthase; very long-chain fatty-acid-coenzyme A ligase 1; Very long-chain-fatty-acid-CoA ligase; VLACS; VLCS

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Gene Aliases: ACSVL1; FACVL1; FATP2; hFACVL1; HsT17226; SLC27A2; Vlac; VLACS; VLCS

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UniProt ID: (Human) O14975, (Rat) P97524, (Mouse) O35488

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Entrez Gene ID: (Human) 11001, (Rat) 65192, (Mouse) 26458

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Function(s)
nucleotide binding long-chain fatty acid-CoA ligase activity long-chain fatty acid transporter activity ATP binding fatty acid transporter activity ligase activity enzyme binding very long-chain fatty acid-CoA ligase activity arachidonate-CoA ligase activity cholate-CoA ligase activity phytanate-CoA ligase activity pristanate-CoA ligase activity receptor binding protein binding catalytic activity acyl-CoA ligase activity succinate-CoA ligase activity 3-oxo-2-(2'-pentenyl)cyclopentane-1-octanoic acid CoA ligase activity fatty acid ligase activity 3-isopropenyl-6-oxoheptanoyl-CoA synthetase activity 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA synthetase activity benzoyl acetate-CoA ligase activity 2,4-dichlorobenzoate-CoA ligase activity pivalate-CoA ligase activity cyclopropanecarboxylate-CoA ligase activity adipate-CoA ligase activity citronellyl-CoA ligase activity mentha-1,3-dione-CoA ligase activity thiophene-2-carboxylate-CoA ligase activity 2,4,4-trimethylpentanoate-CoA ligase activity cis-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity trans-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity branched-chain acyl-CoA synthetase (ADP-forming) activity aryl-CoA synthetase (ADP-forming) activity 3-hydroxypropionyl-CoA synthetase activity perillic acid:CoA ligase (ADP-forming) activity perillic acid:CoA ligase (AMP-forming) activity (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (ADP-forming) activity (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (AMP-forming) activity malonyl-CoA synthetase activity transporter secondary carrier transporter
Process(es)
very long-chain fatty acid metabolic process fatty acid alpha-oxidation long-chain fatty acid metabolic process lipid metabolic process fatty acid metabolic process fatty acid beta-oxidation bile acid biosynthetic process lipid transport bile acid metabolic process fatty acid transport long-chain fatty acid transport fatty acid beta-oxidation using acyl-CoA oxidase very long-chain fatty acid catabolic process long-chain fatty acid import fatty-acyl-CoA biosynthetic process methyl-branched fatty acid metabolic process metabolic process
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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