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Recommended positive controls: MCF-7.
Predicted reactivity: Mouse (98%), Rat (97%), Xenopus laevis (83%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Members of the F-box protein family, such as FBXL17, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: F-box and leucine-rich repeat protein 17; F-box only protein 13; F-box/LRR-repeat protein 17
Gene Aliases: 6330576B01Rik; AI452053; BB073797; C130023C01Rik; FBL17; FBX13; FBXL17; FBXO13
UniProt ID: (Human) Q9UF56, (Mouse) Q9QZN1
Entrez Gene ID: (Human) 64839, (Mouse) 50758
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