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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||KLH conjugated synthetic peptide between 291-320 amino acids from the C-terminal region of human FBXW12|
|Purification||Antigen affinity chromatography|
|Contains||0.09% sodium azide|
|Storage Conditions||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||1:10-1:50|
|Western Blot (WB)||1:1000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
Members of the F-box protein family, such as FBXW12, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603034), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
F-box and WD-40 domain protein 12; F-box and WD-40 domain-containing protein 12; F-box only protein 35; F-box- and WD40-repeat-containing protein; F-box/WD repeat-containing protein 12; FBW12; FBXO12; FBXO35
FBW12; FBXO12; FBXO35; FBXW12