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Proteintech
FCN3 Polyclonal Antibody
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Product Details
11867-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
FCN3 Fusion Protein Ag2449 (20-288 aa encoded by BC020731)
Conjugate
Form
Liquid
Concentration
0.17 mg/mL
Amount
25.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: CLKTQEHPS CPGPRELEAS KVVLLPSCPG APGSPGEKGA PGPQGPPGPP GKMGPKGEPG PRNCRELLSQ GATLSGWYHL CLPEGRALPV FCDMDTEGGG WLVFQRRQDG SVDFFRSWSS YRAGFGNQES EFWLGNENLH QLTLQGNWEL RVELEDFNGN RTFAHYATFR LLGEVDHYQL ALGKFSEGTA GDSLSLHSGR PFTTYDADHD SSNSNCAVIV HGAWWYASCY RSNLNGRYAV SEAAAHKYGI DWASGRGVGH PYRRVRMMLR (20-288 aa encoded by BC020731)
Target Information
H-Ficolin (Hakata antigen, Ficolin-3) is an innate immunity pattern recognition molecule found in human serum. H-Ficolin binds to distinct pathogen-associated molecular patterns (PAMP) formed by carbohydrates (GlcNAc, GalNAc and fucose) activating complement through the lectin pathway by means of the associated MASPs ((MBL)-associated serine proteases). H-Ficolin consists of 35 kDa protein chains associated in triplet subunits which are again associated in high molecular weight oligomers by means of disulfide bonds at the N-terminal region.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Collagen/fibrinogen domain-containing lectin 3 p35; Collagen/fibrinogen domain-containing protein 3; FCN3; ficolin (collagen/fibrinogen domain containing) 3 (Hakata antigen); Ficolin-3; H-ficolin; Hakata antigen; MGC22543; unnamed protein product
Gene Aliases: FCN3; FCNH; HAKA1
UniProt ID: (Human) O75636
Entrez Gene ID: (Human) 8547
complement activation, lectin pathway
activation of membrane attack complex
immune system process
cell surface pattern recognition receptor signaling pathway
proteolysis
complement activation
opsonization
zymogen activation
killing of cells of other organism
recognition of apoptotic cell
innate immune response
negative regulation of viral entry into host cell
protein maturation
defense response to virus
negative regulation of RNA biosynthetic process
positive regulation of opsonization
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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