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FGF1 Polyclonal Antibody
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Product Details
BS-0229R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from mouse FGF1, amino acids 16-80.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
FGF1 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein functions as a modifier of endothelial cell migration and proliferation, as well as an angiogenic factor. It acts as a mitogen for a variety of mesoderm- and neuroectoderm-derived cells in vitro, thus is thought to be involved in organogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Acidic fibroblast growth factor; aFGF; beta-endothelial cell growth factor; ECGF; Endothelial cell growth factor; endothelial cell growth factor, alpha; endothelial cell growth factor, beta; FGF; FGF-1; Fibroblast growth factor; Fibroblast growth factor 1; fibroblast growth factor 1 (acidic); Fibroblast growth factor 1 (heparin binding); H-FGF-a; HBGF-1; Heparin-binding growth factor 1; M-FGF-a; unnamed protein product
Gene Aliases: AFGF; Dffrx; ECGF; ECGF-beta; ECGFA; ECGFB; Fam; FGF-1; FGF-alpha; FGF1; FGFA; GLIO703; HBGF-1; HBGF1
UniProt ID: (Human) P05230, (Rat) P61149, (Mouse) P61148
Entrez Gene ID: (Human) 2246, (Rat) 25317, (Mouse) 14164
angiogenesis
branching involved in ureteric bud morphogenesis
organ induction
signal transduction
positive regulation of cell proliferation
fibroblast growth factor receptor signaling pathway
anatomical structure morphogenesis
positive regulation of endothelial cell migration
neurogenesis
cell differentiation
lung development
regulation of cell migration
positive regulation of cell migration
activation of protein kinase B activity
cellular response to heat
wound healing
positive regulation of MAP kinase activity
positive regulation of MAPK cascade
positive regulation of cholesterol biosynthetic process
positive regulation of angiogenesis
positive regulation of transcription from RNA polymerase II promoter
epithelial cell proliferation
positive regulation of epithelial cell proliferation
positive regulation of cell division
branch elongation involved in ureteric bud branching
positive regulation of ERK1 and ERK2 cascade
mesonephric epithelium development
regulation of endothelial tube morphogenesis
positive regulation of intracellular signal transduction
positive regulation of sprouting angiogenesis
regulation of morphogenesis of an epithelium
regulation of endothelial cell chemotaxis to fibroblast growth factor
positive regulation of protein phosphorylation
cell proliferation
multicellular organism development
positive regulation of transcription, DNA-templated
cardiac muscle cell proliferation
vasculogenesis involved in coronary vascular morphogenesis
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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