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Proteintech
FGF8 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
20711-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Peptide
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.17 mg/mL
Amount
25.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
The antibody is specific to FGF8.
Target Information
Plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration. Required for normal brain, eye, ear and limb development during embryogenesis. Required for normal development of the gonadotropin-releasing hormone (GnRH) neuronal system. Plays a role in neurite outgrowth in hippocampal cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: androgen-induced; androgen-induced growth factor; FGF; Fibroblast growth factor; fibroblast growth factor 6c; fibroblast growth factor 8 (androgen-induced); heparin-binding growth factor 8; MGC149376; unnamed protein product
Gene Aliases: AIGF; FGF-8; Fgf6c; HBGF-8; HH6; KAL6
UniProt ID: (Human) P55075, (Mouse) P37237
Entrez Gene ID: (Human) 2253, (Rat) 29349, (Mouse) 14179
metanephros development
mesonephros development
outflow tract septum morphogenesis
epithelial to mesenchymal transition involved in endocardial cushion formation
response to oxidative stress
signal transduction
gastrulation
motor neuron axon guidance
positive regulation of cell proliferation
gonad development
fibroblast growth factor receptor signaling pathway
response to xenobiotic stimulus
anatomical structure morphogenesis
dorsal/ventral pattern formation
positive regulation of gene expression
forebrain neuron development
central nervous system neuron development
neurogenesis
regulation of cell migration
dorsal/ventral axon guidance
odontogenesis
positive regulation of MAPK cascade
positive regulation of cell differentiation
positive chemotaxis
negative regulation of cardiac muscle tissue development
bone development
neuroepithelial cell differentiation
dopaminergic neuron differentiation
MAPK cascade
patterning of blood vessels
branching involved in ureteric bud morphogenesis
organ induction
kidney development
neural plate morphogenesis
heart looping
blood vessel remodeling
heart morphogenesis
outflow tract morphogenesis
determination of left/right symmetry
heart development
mesodermal cell migration
embryo development ending in birth or egg hatching
telencephalon development
pallium development
subpallium development
forebrain dorsal/ventral pattern formation
cell proliferation in forebrain
signal transduction involved in regulation of gene expression
lung development
male genitalia development
thyroid gland development
otic vesicle formation
midbrain-hindbrain boundary development
embryonic heart tube development
limb morphogenesis
embryonic hindlimb morphogenesis
aorta morphogenesis
inner ear morphogenesis
regulation of odontogenesis of dentin-containing tooth
negative regulation of apoptotic process
negative regulation of neuron apoptotic process
cell fate commitment
positive regulation of G-protein coupled receptor protein signaling pathway
positive regulation of mitotic nuclear division
positive regulation of organ growth
generation of neurons
embryonic neurocranium morphogenesis
forebrain morphogenesis
positive regulation of peptidyl-tyrosine phosphorylation
pharyngeal system development
corticotropin hormone secreting cell differentiation
thyroid-stimulating hormone-secreting cell differentiation
lung morphogenesis
branching involved in salivary gland morphogenesis
positive regulation of ERK1 and ERK2 cascade
cell migration involved in mesendoderm migration
larynx morphogenesis
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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