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Proteintech
FGF8 Polyclonal Antibody
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Product Details
20711-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Peptide
Conjugate
Form
Liquid
Concentration
0.17 mg/mL
Amount
25.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
The antibody is specific to FGF8.
Target Information
Plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration. Required for normal brain, eye, ear and limb development during embryogenesis. Required for normal development of the gonadotropin-releasing hormone (GnRH) neuronal system. Plays a role in neurite outgrowth in hippocampal cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: AIGF; androgen-induced; Androgen-induced growth factor; FGF; FGF-8; Fibroblast growth factor; Fibroblast growth factor 8; fibroblast growth factor 8 (androgen-induced); HBGF-8; Heparin-binding growth factor 8; MGC149376
Gene Aliases: AIGF; FGF-8; FGF8; HBGF-8; HH6; KAL6
UniProt ID: (Human) P55075, (Mouse) P37237
Entrez Gene ID: (Human) 2253, (Rat) 29349, (Mouse) 14179
MAPK cascade
patterning of blood vessels
metanephros development
branching involved in ureteric bud morphogenesis
organ induction
kidney development
mesonephros development
neural plate morphogenesis
heart looping
blood vessel remodeling
heart morphogenesis
outflow tract septum morphogenesis
outflow tract morphogenesis
epithelial to mesenchymal transition involved in endocardial cushion formation
apoptotic process
response to oxidative stress
signal transduction
determination of left/right symmetry
gastrulation
heart development
motor neuron axon guidance
mesodermal cell migration
cell proliferation
positive regulation of cell proliferation
gonad development
fibroblast growth factor receptor signaling pathway
response to xenobiotic stimulus
anatomical structure morphogenesis
embryo development ending in birth or egg hatching
dorsal/ventral pattern formation
positive regulation of gene expression
telencephalon development
pallium development
subpallium development
forebrain dorsal/ventral pattern formation
cell proliferation in forebrain
forebrain neuron development
central nervous system neuron development
neurogenesis
signal transduction involved in regulation of gene expression
cell differentiation
lung development
regulation of cell migration
male genitalia development
thyroid gland development
otic vesicle formation
midbrain-hindbrain boundary development
dorsal/ventral axon guidance
embryonic heart tube development
limb morphogenesis
embryonic hindlimb morphogenesis
organ growth
aorta morphogenesis
inner ear morphogenesis
odontogenesis
regulation of odontogenesis of dentin-containing tooth
negative regulation of apoptotic process
positive regulation of MAPK cascade
negative regulation of neuron apoptotic process
cell fate commitment
positive regulation of cell differentiation
positive regulation of G-protein coupled receptor protein signaling pathway
positive regulation of mitotic nuclear division
positive regulation of organ growth
generation of neurons
embryonic neurocranium morphogenesis
forebrain morphogenesis
positive chemotaxis
neuron apoptotic process
positive regulation of cell division
negative regulation of cardiac muscle tissue development
pharyngeal system development
corticotropin hormone secreting cell differentiation
thyroid-stimulating hormone-secreting cell differentiation
bone development
lung morphogenesis
branching involved in salivary gland morphogenesis
neuroepithelial cell differentiation
positive regulation of ERK1 and ERK2 cascade
dopaminergic neuron differentiation
stem cell proliferation
cell migration involved in mesendoderm migration
larynx morphogenesis
mitotic nuclear division
positive regulation of stem cell proliferation
response to organic cyclic compound
BMP signaling pathway
response to drug
canonical Wnt signaling pathway
multicellular organism development
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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