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          • Primary Antibodies ›
          • FGF8 Antibodies

          Invitrogen

          FGF8 Polyclonal Antibody

          View all (16) FGF8 antibodies

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          Cite FGF8 Polyclonal Antibody

          Additional Information:
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          • Antibody Testing Data (3)
          FGF8 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          FGF8 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          FIGURE: 1 / 3

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          FGF8 Antibody (PA5-79259) in IHC (P)

          Immunohistochemical analysis of FGF8 in paraffin-embedded section of human ovarian cancer tissue. Heat mediated antigen retrieval was performed in citrate buffer (pH6, epitope retrieval solution) for 20 mins. The tissue section was blocked with 10% goat serum. The tissue section was then incubated with 1μg/mL rabbit anti-FGF8 antibody (Product # PA5-79259) overnight at 4°C. Biotinylated goat anti-rabbit IgG... View More {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          View Product

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          FGF8 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          FGF8 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          FGF8 Antibody in Western Blot (WB)
          FGF8 Polyclonal Antibody

          Product Details

          PA5-79259

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          0.1-0.5 µg/mL
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          0.5-1 µg/mL
          -
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          A synthetic peptide corresponding to a sequence at the C-terminus of human FGF8 (163-185aa FMKRLPRGHHTTEQSLRFEFLNY).
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Lyophilized

          Concentration

          500 µg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS with 5mg BSA

          Contains

          0.05mg sodium azide, 0.05mg thimerosal

          Storage conditions

          -20°C

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2746375

          Product Specific Information

          Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.

          Positive Control - WB: Rat Ovary Tissue. IHC: Rat Ovary Tissue, human ovarian cancer tissue.

          Target Information

          Plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration. Required for normal brain, eye, ear and limb development during embryogenesis. Required for normal development of the gonadotropin-releasing hormone (GnRH) neuronal system. Plays a role in neurite outgrowth in hippocampal cells.

          ⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: AIGF; androgen-induced; Androgen-induced growth factor; FGF; FGF-8; Fibroblast growth factor; Fibroblast growth factor 8; fibroblast growth factor 8 (androgen-induced); HBGF-8; Heparin-binding growth factor 8; MGC149376

          View more View less

          Gene Aliases: AIGF; FGF-8; FGF8; HBGF-8; HH6; KAL6

          View more View less

          UniProt ID: (Human) P55075, (Mouse) P37237

          View more View less

          Entrez Gene ID: (Human) 2253, (Rat) 29349, (Mouse) 14179

          View more View less

          Function(s)
          type 1 fibroblast growth factor receptor binding type 2 fibroblast growth factor receptor binding growth factor activity chemoattractant activity receptor binding fibroblast growth factor receptor binding growth factor intercellular signal molecule
          Process(es)
          MAPK cascade patterning of blood vessels metanephros development branching involved in ureteric bud morphogenesis organ induction kidney development mesonephros development neural plate morphogenesis heart looping blood vessel remodeling heart morphogenesis outflow tract septum morphogenesis outflow tract morphogenesis epithelial to mesenchymal transition involved in endocardial cushion formation apoptotic process response to oxidative stress signal transduction determination of left/right symmetry gastrulation heart development motor neuron axon guidance mesodermal cell migration cell proliferation positive regulation of cell proliferation gonad development fibroblast growth factor receptor signaling pathway response to xenobiotic stimulus anatomical structure morphogenesis embryo development ending in birth or egg hatching dorsal/ventral pattern formation positive regulation of gene expression telencephalon development pallium development subpallium development forebrain dorsal/ventral pattern formation cell proliferation in forebrain forebrain neuron development central nervous system neuron development neurogenesis signal transduction involved in regulation of gene expression cell differentiation lung development regulation of cell migration male genitalia development thyroid gland development otic vesicle formation midbrain-hindbrain boundary development dorsal/ventral axon guidance embryonic heart tube development limb morphogenesis embryonic hindlimb morphogenesis organ growth aorta morphogenesis inner ear morphogenesis odontogenesis regulation of odontogenesis of dentin-containing tooth negative regulation of apoptotic process positive regulation of MAPK cascade negative regulation of neuron apoptotic process cell fate commitment positive regulation of cell differentiation positive regulation of G-protein coupled receptor protein signaling pathway positive regulation of mitotic nuclear division positive regulation of organ growth generation of neurons embryonic neurocranium morphogenesis forebrain morphogenesis positive chemotaxis neuron apoptotic process positive regulation of cell division negative regulation of cardiac muscle tissue development pharyngeal system development corticotropin hormone secreting cell differentiation thyroid-stimulating hormone-secreting cell differentiation bone development lung morphogenesis branching involved in salivary gland morphogenesis neuroepithelial cell differentiation positive regulation of ERK1 and ERK2 cascade dopaminergic neuron differentiation stem cell proliferation cell migration involved in mesendoderm migration larynx morphogenesis mitotic nuclear division positive regulation of stem cell proliferation response to organic cyclic compound BMP signaling pathway response to drug canonical Wnt signaling pathway multicellular organism development
          It has to be done as per old AB suggested Products section.

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