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Proteintech
FGFBP1 Polyclonal Antibody
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Product Details
25006-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
FGFBP1 Fusion Protein Ag6357 (1-234 aa encoded by BC003628)
Conjugate
Form
Liquid
Concentration
0.4 mg/mL
Amount
60 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MKICSLTLL SFLLLAAQVL LVEGKKKVKN GLHSKVVSEQ KDTLGNTQIK QKSRPGNKGK FVTKDQANCR WAATEQEEGI SLKVECTQLD HEFSCVFAGN PTSCLKLKDE RVYWKQVARN LRSQKDICRY SKTAVKTRVC RKDFPESSLK LVSSTLFGNT KPRKEKTEMS PREHIKGKET TPSSLAVTQT MATKAPECVE DPDMANQRKT ALEFCGETWS SLCTFFLSIV QDTSC (1-234 aa encoded by BC003628)
Target Information
FGFBP1 encodes a secreted fibroblast growth factor carrier protein. The encoded protein plays a critical role in cell proliferation, differentiation and migration by binding to fibroblast growth factors and potentiating their biological effects on target cells. The encoded protein may also play a role in tumor growth as an angiogenic switch molecule, and expression of this gene has been associated with several types of cancer including pancreatic and colorectal adenocarcinoma. A pseudogene of this gene is also located on the short arm of chromosome 4.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 17 kDa HBGF-binding protein; 17 kDa heparin-binding growth factor-binding protein; FGF-binding protein 1; FGF-BP; Fibroblast growth factor-binding protein 1; heparin-binding growth factor binding protein; unnamed protein product
Gene Aliases: FGF-BP; FGF-BP1; FGFBP; FGFBP-1; FGFBP1; HBP17
UniProt ID: (Human) Q14512, (Mouse) O70514
Entrez Gene ID: (Human) 9982, (Mouse) 14181
signal transduction
cell-cell signaling
negative regulation of cell proliferation
fibroblast growth factor receptor signaling pathway
positive regulation of fibroblast growth factor receptor signaling pathway
myoblast proliferation
positive regulation of cell migration involved in sprouting angiogenesis
positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis
positive regulation of myoblast proliferation
positive regulation of defense response to virus by host
positive regulation of cell proliferation
mitophagy in response to mitochondrial depolarization
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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