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Proteintech
FIP1L1 Polyclonal Antibody
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Product Details
12276-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
FIP1L1 Fusion Protein Ag2921 (1-350 aa encoded by BC017724)
Conjugate
Form
Liquid
Concentration
0.24 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MSAGEVERL VSELSGGTGG DEEEEWLYGD ENEVERPEEE NASANPPSGI EDETAENGVP KPKVTETEDD SDSDSDDDED DVHVTIGDIK TGAPQYGSYG TAPVNLNIKT GGRVYGTTGT KVKGVDLDAP GSINGVPLLE VDLDSFEDKP WRKPGADLSD YFNYGFNEDT WKAYCEKQKR IRMGLEVIPV TSTTNKITAE DCTMEVTPGA EIQDGRFNLF KVQQGRTGNS EKETALPSTK AEFTSPPSLF KTGLPPSRNS TSSQSQTSTA SRKANSSVGK WQDRYGRAES PDLRRLPGAI DVIGQTITIS RVEGRRRANE NSNIQVLSER SATEVDNNFS KPPPFFPPGA P (1-350 aa encoded by BC017724)
Target Information
FIP1L1 is a component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. FIP1L1 contributes to poly(A) site recognition and stimulates poly(A) addition. It binds to U-rich RNA sequence elements surrounding the poly(A) site. FIP1L1 may act to tether poly(A) polymerase to the CPSF complex.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DKFZp586K0717; Factor interacting with PAP; FIP1 like 1; FIP1-like 1 protein; FIP1L1 cleavage and polyadenylation specific factor subunit; FLJ33619; hFip1; Pre-mRNA 3'-end-processing factor FIP1; Rearranged in hypereosinophilia
Gene Aliases: 1300019H17Rik; FIP1; FIP1L1; hFip1; RHE; Rje
UniProt ID: (Human) Q6UN15, (Mouse) Q9D824, (Rat) Q5U317
Entrez Gene ID: (Human) 81608, (Mouse) 66899, (Rat) 289582
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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