Immunogen sequence: MEQLLRAEL RTATLRAFGG PGAGCISEGR AYDTDAGPVF VKVNRRTQAR QMFEGEVASL EALRSTGLVR VPRPMKVIDL PGGGAAFVME HLKMKSLSSQ ASKLGEQMAD LHLYNQKLRE KLKEEENTVG RRGEGAEPQY VDKFGFHTVT CCGFIPQVNE WQDDWPTFFA RHRLQAQLDL IEKDYADREA RELWSRLQVK IPDLFCGLEI VPALLHGDLW SGNVAEDDVG PIIYDPASFY GHSEFELAIA LMFGGFPRSF FTAYHRKIPK APGFDQRLLL YQLFNYLNHW NHFGREYRSP SLGTMRRLLK (1-309 aa encoded by BC042680)
FN3K catalyzes phosphorylation of fructosamines formed by glycation, the nonenzymatic reaction of glucose with primary amines followed by Amadori rearrangement. Phosphorylation of fructosamines may initiate metabolism of the modified amine and result in deglycation of glycated proteins.
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Protein Aliases: Fructosamine-3-kinase; Protein-psicosamine 3-kinase FN3K; Protein-ribulosamine 3-kinase FN3K
Gene Aliases: 2310074G21Rik; FN3K
Molecular Function: kinase