Search
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Proteintech
FNIP1 Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Product Details
28380-1-AP
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
FNIP1 Fusion Protein Ag28976
Conjugate
Form
Liquid
Concentration
367 µg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
Aliquoting is unnecessary for -20°C storage.
Target Information
FNIP1 encodes a protein that binds to the tumor suppressor protein folliculin and to AMP-activated protein kinase (AMPK). The encoded protein participates in the regulation of cellular metabolism and nutrient sensing by modulating the AMPK and target of rapamycin signaling pathways. This gene has a closely related paralog that encodes a protein with similar binding activities. Both related proteins also associate with the molecular chaperone heat shock protein-90 (Hsp90) and negatively regulate its ATPase activity and facilitate its association with folliculin. Diseases associated with FNIP1 include Birt-Hogg-Dube Syndrome and Pleural Disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: Folliculin-interacting protein 1
Gene Aliases: A730024A03Rik; AI838773; AW557298; FNIP1; KIAA1961
UniProt ID: (Human) Q8TF40, (Mouse) Q68FD7
Entrez Gene ID: (Human) 96459, (Mouse) 216742, (Rat) 100362347
negative regulation of transcription from RNA polymerase II promoter
regulation of protein phosphorylation
positive regulation of protein phosphorylation
immature B cell differentiation
positive regulation of B cell apoptotic process
cellular response to starvation
TOR signaling
negative regulation of TOR signaling
positive regulation of peptidyl-serine phosphorylation
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
positive regulation of GTPase activity
regulation of pro-B cell differentiation
positive regulation of protein complex assembly
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support