Recommended positive controls: 293T, A431, HeLa, HepG2, A549, H1299, HCT116.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
FOXN1 is a 648 amino acid protein belonging to the winged helix/forkhead family It contains 1 fork-head DNA-binding domain and is a transcriptional regulator involved in development. FOXN1 is involved in directing lineage choices of multi-potential progenitor epithelial cells and controls important regulating genes of lympho-epithelial interactions. It modulates keratinocyte differentiation in hair follicles and nail apparatus and its defects lead to T-cell immunodeficiency congenital alopecia, nail dystrophy, macroscopic nudity and an inborn dysgenesis of the thymus.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Forkhead box protein N1; Hepatocyte nuclear factor 3 forkhead homolog 11; HFH-11; HNF-3/forkhead homolog 11; JTK1; Rowett nude; winged helix nude; winged-helix nude; Winged-helix transcription factor nude
Gene Aliases: D11Bhm185e; Fkh19; FKHL20; FOXN1; HFH-11; Hfh11; nu; nude; Rnu; RONU; WHN