Percent identity with other species by BLAST analysis: Human, Chimpanzee, Gorilla, Monkey (100%) Orangutan (94%) Gibbon (89%).
Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: FML2_HUMAN; FMLP-R-II; FMLP-related receptor II; FMLPY; Formyl peptide receptor 3; Formyl peptide receptor-like 2; FPR3; FPRH1; FPRH2; FPRL2; N-formyl peptide receptor 3; N-formyl receptor-like 2; RMLP-R-I
Gene Aliases: FML2_HUMAN; FMLP-R-II; FMLPY; FPR3; FPRH1; FPRH2; FPRL2; RMLP-R-I
UniProt ID: (Human) P25089
Entrez Gene ID: (Human) 2359